Dr Rehan Junejo
Dr Rehan Junejo
Senior Lecturer Physiology
My profile
Biography
Senior Lecturer in Human Physiology in the Department of Life Sciences with pedagogic responsibilities to help support undergraduate and postgraduate teaching. Research interests are in integrative neural and metabolic control of cerebrovascular and cardiovascular systems investigating basic and translational research questions in healthy and diseased populations. Research fellow at Liverpool Centre for Cardiovascular Science (University of Liverpool and Liverpool Heart and Chest Hospital). I serve on Hypertension’s editorial board as an early career editorial fellow and peer review manuscripts for a number of scientific journals (Experimental Physiology, European Journal of Applied Physiology, Physiological Reports, Journal of Applied Physiology, American Journal of Physiology-Heart and Circulatory Physiology, EuroPace and others).
I am currently seeking highly motivated research students who are interested in studying basic and/or translational questions pertaining to cerebrovascular and/or cardiovascular control in humans. Prospective research students (MRes and PhD) are encouraged to directly contact me to discuss potential projects / opportunities.
Academic and professional qualifications
Fellowship of Advance Higher Education 2022
PhD Physiology; University of Birmingham 2017
MSc Integrated Physiology; University of Nottingham 2011
MBBS; Liaquat University of Medical and Health Sciences 2009
Research outputs
Prizes and awards
Caroline tum Suden / Frances Hellebrandt Award for Meritorious Research - 2015
Visiting and honorary positions
Research Fellow - Liverpool Centre for Cardiovascular Science and University of Liverpool (2018 - )
Membership of professional associations
The Physiological Society (2012 - )
American Physiological Society (2013 - )
Cerebrovascular Research Network (2018 - )
Research Outputs
Ball, J. D., Hills, E., Altaf, A., Ramesh, P., Green, M., Surti, F. B., … & C Beishon, L. (2024). Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement. Journal of Cerebral Blood Flow & Metabolism, 0271678X241270452.
Walsh, H.J., Junejo, R.T., Lip, G.Y. and Fisher, J.P., 2024. The effect of hypertension on cerebrovascular carbon dioxide reactivity in atrial fibrillation patients. Hypertension Research, pp.1-10.
Junejo, R.T., Gupta, D., Snowdon, R.L., Lip, G.Y. and Fisher, J.P., 2024. Relationship of Warfarin and Apixaban with Vascular Function in Patients with Atrial Fibrillation. Journal of Vascular Research, 61(2), pp.59-67.
Alali, M.H., Lucas, R.A., Junejo, R.T. and Fisher, J.P., 2022. Impact of acute dynamic exercise and arterial shear rate modification on radial artery low-flow mediated constriction in young men. European Journal of Applied Physiology, pp.1-11.
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P. and Lip, G.Y.H., 2021. Assessment of cardiac autonomic function in patients with permanent and paroxysmal atrial fibrillation. European Heart Journal, 42(Supplement_1), pp.ehab724-0426.
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P. and Lip, G.Y.H., 2021. Association between atrial high rate episode burden and autonomic and vascular function in patients with implanted cardiac device. European Heart Journal, 42(Supplement_1), pp.ehab724-0282.
Khan, A.A., Junejo, R.T., Alsharari, R., Thomas, G.N., Fisher, J.P. and Lip, G.Y., 2021. A greater burden of atrial fibrillation is associated with worse endothelial dysfunction in hypertension. Journal of Human Hypertension, 35(8), pp.667-677.
Khan, A., Junejo, R., Fisher, J., Thomas, N. and Lip, G., 2021. 86 Cardiac autonomic function influences in atrial fibrillation and hypertension.
Khan, A., Alsharari, R., Junejo, R., Thomas, N., Fisher, J. and Lip, G., 2021. 83 Autonomic and vascular function characteristics in patients with atrial high rate episodes.
AlSalahi, S.E., Junejo, R.T., Bradley, C., Balanos, G.M., Siebenmann, C. and Fisher, J.P., 2021. The middle cerebral artery blood velocity response to acute normobaric hypoxia occurs independently of changes in ventilation in humans. Experimental Physiology, 106(4), pp.861-867.
Khan, A., Junejo, R., Thomas, N., Fisher, J. and Lip, G., 2021. 101 Role of cardiac autonomic function in pathophysiology of permanent AF. Cardiac rhythm management.
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P. and Lip, G.Y., 2021. Heart rate variability in patients with atrial fibrillation and hypertension. European journal of clinical investigation, 51(1), p.e13361.
Alali, M.H., Vianna, L.C., Lucas, R.A., Junejo, R.T. and Fisher, J.P., 2020. Impact of whole body passive heat stress and arterial shear rate modification on radial artery function in young men. Journal of Applied Physiology, 129(6), pp.1373-1382.
Junejo, R.T., 2020. Muscle afferent contributions to exercise intolerance in heart failure. The Journal of Physiology.
Junejo, R.T., Lip, G.Y. and Fisher, J.P., 2020. Cerebrovascular dysfunction in atrial fibrillation. Frontiers in physiology, 11, p.1066.
Junejo, R.T., Braz, I.D., Lucas, S.J., van Lieshout, J.J., Phillips, A.A., Lip, G.Y. and Fisher, J.P., 2020. Neurovascular coupling and cerebral autoregulation in atrial fibrillation. Journal of Cerebral Blood Flow & Metabolism, 40(8), pp.1647-1657.
Junejo, R.T., Ray, C.J. and Marshall, J.M., 2020. Prostaglandin contribution to postexercise hyperemia is dependent on tissue oxygenation during rhythmic and isometric contractions. Physiological reports, 8(12), p.e14471.
AlSalahi, S.E., Braz, I.D., Ahmed, A., Junejo, R.T. and Fisher, J.P., 2020. Human cerebrovascular responses to diving are not related to facial cooling. Experimental physiology, 105(6), pp.940-949.
Junejo, R.T., May, S., Alsalahi, S., Alali, M., Ogoh, S. and Fisher, J.P., 2020. Cerebrovascular carbon dioxide reactivity and flow-mediated dilation in young healthy South Asian and Caucasian European men. American Journal of Physiology-Heart and Circulatory Physiology, 318(4), pp.H756-H763.
Junejo, R.T., Braz, I.D., Lucas, S.J., van Lieshout, J.J., Lip, G.Y. and Fisher, J.P., 2019. Impaired cerebrovascular reactivity in patients with atrial fibrillation. Journal of the American College of Cardiology, 73(10), pp.1230-1232.
Junejo, R.T., Phillips, A., Lucas, S.J., van Lieshout, J.J., Lip, G.Y. and Fisher, J.P., 2019. Neurovascular coupling is blunted in atrial fibrillation. The FASEB Journal, 33(S1), pp.696-3.
Junejo, R.T., Ray, C.J. and Marshall, J.M., 2019. Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography. European journal of applied physiology, 119(3), pp.665-674.
Ormshaw, N.G., Junejo, R.T. and Marshall, J.M., 2018. Forearm vasodilator responses to environmental stress and reactive hyperaemia are impaired in young South Asian men. European Journal of Applied Physiology, 118(5), pp.979-988.
Junejo, R.T., 2017. Contribution of oxygen-dependent mechanisms to vascular responses of exercise in young and older men: the role of prostaglandins and adenosine (Doctoral dissertation, University of Birmingham).
Junejo, R.T., Ray, C.J., Lucas, S.J. and Marshall, J.M., 2016. Investigation into effects of supplementary O2 on tissue oxygenation during isometric handgrip in the ipsilateral and contralateral limb in young (Y) and older (O) men using Near Infra Red Spectroscopy (NIRS). The FASEB Journal, 30, pp.761-9.
Aiku, A.O., Ormshaw, N.G., Junejo, R.T., Martin, U. and Marshall, J.M., 2016. Both Endothelium‐Dependent Dilatation Responses And Muscle Vasodilator Responses To Environmental Stressors Are Impaired In Young Black Africans And May Contribute To Their Predisposition To Develop Hypertension. The FASEB Journal, 30, pp.1206-5.
Ormshaw, N., Junejo, R. and Marshall, J., 2015. PD. 03. Both endothelium-dependent dilator responses and muscle vasodilator responses to environmental stressors are impaired in Young South Asians and may predispose to hypertension. Journal of Human Hypertension, 29(10), pp.644-645.
Junejo, R., Ray, C. and Marshall, J., 2015. O2 dependent contributions of prostaglandins (PGI2 PGE2) to exercise hyperaemia in young (Y) and older (O) men. The FASEB Journal, 29, pp.994-19.
Ray, C., Junejo, R. and Marshall, J., 2015. Does Adenosine make an O2 Dependent Contribution to Exercise Hyperaemia?. The FASEB Journal, 29, pp.994-14.
Junejo, R., Ray, C. and Marshall, J., 2015. Prostaglandins (PGs) Contribute in an O2 Dependent Manner to Reflex Vasoconstriction in Exercise. The FASEB Journal, 29, pp.994-20.
Marshall, J., Junejo, R., D’Souza, F. and Ray, C., 2015. Effects of breathing O2 at different concentrations on reactive oxygen species (ROS) and endothelium dependent dilatation. The FASEB Journal, 29, pp.787-4.
Junejo, R., Ray, C. and Marshall, J., 2014. Prostaglandins contribute in an O2‐dependent manner to exercise hyperaemia following rhythmic and isometric handgrip exercise in young and older healthy subjects (1106.4). The FASEB Journal, 28, pp.1106-4.
Junejo, R.T., Pavliv, F.N., Ray, C.J. and Marshall, J.M., Comparison between automated inflation and manual inflation for forearm blood flow measurements made with venous occlusion plethysmography in humans.
Media
Christian Eriksen: why do cardiac arrests happen in some athletes?
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Chapters in books
Mahmoud, A., Junejo, R. (2024) 'Oxidative Stress in Cardiovascular Diseases.' Biomarkers of Oxidative Stress. Springer, Cham,
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Reports
Fielder, S., Barnes, C., Ormesher, L., Junejo, R., Arrowsmith, S., Heazell, A. The effect of the use of e-cigarettes during pregnancy on maternal, fetal and infant health outcomes: A scoping review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols.
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Journal articles
Junejo, R.T., Gupta, D., Snowdon, R.L., Lip, G.Y.H., Fisher, J.P. (2024) 'Relationship of Warfarin and Apixaban with Vascular Function in Patients with Atrial Fibrillation.' Journal of Vascular Research, pp. 1-9.
Ball, J.D., Hills, E., Altaf, A., Ramesh, P., Green, M., Surti, F.B., Minhas, J.S., Robinson, T.G., Bond, B., Lester, A., Hoiland, R., Klein, T., Liu, J., Nasr, N., Junejo, R.T., Müller, M., Lecchini-Visintini, A., Mitsis, G., Burma, J.S., Smirl, J.D., Pizzi, M.A., Manquat, E., Lucas, S.J., Mullinger, K.J., Mayhew, S., Bailey, D.M., Rodrigues, G., Soares, P.P., Phillips, A.A., Prokopiou, P.C., C Beishon, L. (2024) 'Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: a systematic review and consensus agreement.' Journal of Cerebral Blood Flow and Metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism,
Walsh, H.J., Junejo, R.T., Lip, G.Y.H., Fisher, J.P. (2024) 'The effect of hypertension on cerebrovascular carbon dioxide reactivity in atrial fibrillation patients.' Hypertension Research,
Walsh, H., Junejo, R., Lip, G., Fisher, J. (2024) 'Cerebrovascular Conductance Responses to Carbon Dioxide are Attenuated by the Presence of Hypertension in Patients with Atrial Fibrillation.' Physiology, 39(S1)
Alali, M.H., Lucas, R.A.I., Junejo, R.T., Fisher, J.P. (2022) 'Impact of acute dynamic exercise and arterial shear rate modification on radial artery low-flow mediated constriction in young men.' European Journal of Applied Physiology, 122(8) pp. 1885-1895.
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P., Lip, G.Y.H. (2021) 'Association between atrial high rate episode burden and autonomic and vascular function in patients with implanted cardiac device.' European Heart Journal, 42(Supplement_1)
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P., Lip, G.Y.H. (2021) 'Assessment of cardiac autonomic function in patients with permanent and paroxysmal atrial fibrillation.' European Heart Journal, 42(Supplement_1)
AlSalahi, S., Junejo, R., Bradley, C., Balanos, G., Siebenmann, C., Fisher, J. (2021) 'The middle cerebral artery blood velocity response to acute normobaric hypoxia occurs independently of changes in ventilation in humans.' Experimental Physiology, 106(4) pp. 861-867.
Junejo, R.T. (2020) 'Muscle afferent contributions to exercise intolerance in heart failure.' The Journal of Physiology, 599(3) pp. 733-734.
Alali, M.H., Vianna, L.C., Lucas, R.A.I., Junejo, R.T., Fisher, J.P. (2020) 'Impact of whole-body passive heat stress and arterial shear rate modification on radial artery function in young men.' Journal of Applied Physiology, 129(6) pp. 1373-1382.
Junejo, R.T., Lip, G.Y.H., Fisher, J.P. (2020) 'Cerebrovascular Dysfunction in Atrial Fibrillation.' Frontiers in Physiology, 11
Khan, A.A., Junejo, R.T., Thomas, G.N., Fisher, J.P., Lip, G.Y.H. (2020) 'Heart rate variability in patients with atrial fibrillation and hypertension.' European Journal of Clinical Investigation, 51(1) pp. e13361-e13361.
Khan, A.A., Junejo, R.T., Alsharari, R., Thomas, G.N., Fisher, J.P., Lip, G.Y.H. (2020) 'A greater burden of atrial fibrillation is associated with worse endothelial dysfunction in hypertension.' Journal of Human Hypertension, 35(8) pp. 667-677.
Junejo, R.T., Ray, C.J., Marshall, J.M. (2020) 'Prostaglandin contribution to postexercise hyperemia is dependent on tissue oxygenation during rhythmic and isometric contractions.' Physiological Reports, 8(12)
AlSalahi, S.E., Braz, I.D., Ahmed, A., Junejo, R.T., Fisher, J.P. (2020) 'Human cerebrovascular responses to diving are not related to facial cooling.' Experimental Physiology, 105(6) pp. 940-949.
Junejo, R.T., May, S., Alsalahi, S., Alali, M., Ogoh, S., Fisher, J.P. (2020) 'Cerebrovascular carbon dioxide reactivity and flow-mediated dilation in young healthy South Asian and Caucasian European men.' American Journal of Physiology: Heart and Circulatory Physiology, 318(4) pp. H756-H763.
Junejo, R.T., Braz, I.D., Lucas, S.J.E., van Lieshout, J.J., Lip, G.Y.H., Fisher, J.P. (2019) 'Correction to: Impaired Cerebrovascular Reactivity in Patients With Atrial Fibrillation (vol 73, pg 1230, 2019).' Journal of the American College of Cardiology, 74(15) pp. 2014-2014.
Junejo, R.T., Braz, I.D., Lucas, S.J.E., van Lieshout, J.J., Phillips, A.A., Lip, G.Y.H., Fisher, J.P. (2019) 'Neurovascular coupling and cerebral autoregulation in atrial fibrillation.' Journal of Cerebral Blood Flow and Metabolism, 40(8) pp. 1647-1657.
Junejo, R.T., Braz, I.D., Lucas, S.J.E., van Lieshout, J.J., Lip, G.Y.H., Fisher, J.P. (2019) 'Impaired Cerebrovascular Reactivity in Patients With Atrial Fibrillation.' Journal of the American College of Cardiology, 73(10) pp. 1230-1232.
Junejo, R.T., Ray, C.J., Marshall, J.M. (2019) 'Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography.' European Journal of Applied Physiology, 119(3) pp. 665-674.
Ormshaw, N.G., Junejo, R.T., Marshall, J.M. (2018) 'Forearm vasodilator responses to environmental stress and reactive hyperaemia are impaired in young South Asian men.' European Journal of Applied Physiology, 118(5) pp. 979-988.
Junejo, R., Ray, C., Marshall, J. (2014) 'Prostaglandins contribute in an O2‐dependent manner to exercise hyperaemia following rhythmic and isometric handgrip exercise in young and older healthy subjects (1106.4).' The FASEB Journal, 28(S1)
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Conference papers
Giles, A. (2024) 'The cardiovascular implication for exercise intolerance and dyspnoea in electronic cigarettes smokers.'
Phillips, O., Junejo, R., Degens, H., Mahmoud, A. (2024) 'Does electronic cigarette use adversely affect cardiac autonomic function?.' 1. 3/4/2024 - 4/4/2024. Northumbria University Library, pp. 69-69.
Junejo, R., Phillips, O. (2024) 'BS26 Electronic cigarettes adversely affect endothelial health and attenute brachial artery flow mediated dilation.' In British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024. BMJ Publishing Group Ltd and British Cardiovascular Society, pp. A264.1-A264.
Khan, A., Junejo, R., Fisher, J., Thomas, N., Lip, G. (2021) '86 Cardiac autonomic function influences in atrial fibrillation and hypertension.' In British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021. BMJ Publishing Group Ltd and British Cardiovascular Society,
Khan, A., Junejo, R., Thomas, N., Fisher, J., Lip, G. (2021) '101 Role of cardiac autonomic function in pathophysiology of permanent AF.' In British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021. BMJ Publishing Group Ltd and British Cardiovascular Society,
Khan, A., Alsharari, R., Junejo, R., Thomas, N., Fisher, J., Lip, G. (2021) '83 Autonomic and vascular function characteristics in patients with atrial high rate episodes.' In British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021. BMJ Publishing Group Ltd and British Cardiovascular Society,
Junejo, R.T., Phillips, A., Lucas, S.J.E., van Lieshout, J.J., Lip, G.Y.H., Fisher, J.P. (2019) 'Neurovascular Coupling is Blunted in Atrial Fibrillation.' In Experimental Biology Meeting (EB). 33. Orlando, FL, 6/4/2019 - 9/4/2019. WILEY,
Aiku, A.O., Ormshaw, N.G., Junejo, R.T., Martin, U., Marshall, J.M. (2016) 'Both Endothelium-Dependent Dilatation Responses And Muscle Vasodilator Responses To Environmental Stressors Are Impaired In Young Black Africans And May Contribute To Their Predisposition To Develop Hypertension.' In Experimental Biology Meeting. 30. San Diego, CA, 2/4/2016 - 6/4/2016. FEDERATION AMER SOC EXP BIOL,
Junejo, R.T., Ray, C.J., Lucas, S.J.E., Marshall, J.M. (2016) 'Investigation into effects of supplementary O-2 on tissue oxygenation during isometric handgrip in the ipsilateral and contralateral limb in young (Y) and older (O) men using Near Infra Red Spectroscopy (NIRS).' In Experimental Biology Meeting. 30. San Diego, CA, 2/4/2016 - 6/4/2016. FEDERATION AMER SOC EXP BIOL,
Ormshaw, N., Junejo, R., Marshall, J. (2015) 'Both endothelium-dependent dilator responses and muscle vasodilator responses to environmental stressors are impaired in Young South Asians and may predispose to hypertension.' 29. NATURE PUBLISHING GROUP, pp. 644-644.
Junejo, R., Ray, C., Marshall, J. (2015) 'Prostaglandins (PGs) Contribute in an O-2 Dependent Manner to Reflex Vasoconstriction in Exercise.' In Experimental Biology Meeting. 29. Boston, MA, 28/3/2015 - 1/4/2015. FEDERATION AMER SOC EXP BIOL,
Junejo, R., Ray, C., Marshall, J. (2015) 'O-2 Dependent Contributions of Prostaglandins (PGI(2) PGE(2)) to Exercise Hyperaemia in Young (Y) and Older (O) Men.' In Experimental Biology Meeting. 29. Boston, MA, 28/3/2015 - 1/4/2015. FEDERATION AMER SOC EXP BIOL,
Ray, C., Junejo, R., Marshall, J. (2015) 'Does Adenosine make an O-2 Dependent Contribution to Exercise Hyperaemia?.' In Experimental Biology Meeting. 29. Boston, MA, 28/3/2015 - 1/4/2015. FEDERATION AMER SOC EXP BIOL,
Marshall, J., Junejo, R., D'Souza, F., Ray, C. (2015) 'Effects of Breathing O-2 at different Concentrations on Reactive Oxygen Species (ROS) and Endothelium Dependent Dilatation.' In Experimental Biology Meeting. 29. Boston, MA, 28/3/2015 - 1/4/2015. FEDERATION AMER SOC EXP BIOL,