Dr Ehsan Kharati Koopaei
Dr Ehsan Kharati Koopaei FHEA, PGCert
Early Career Researchers (ECR) Representative-Senior Lecturer (Associate Professor) in Statistics/Data Science
My profile
Biography
I am a senior lecturer in Statistics/Data science (or Associate Professor as known in some other higher education’s institutes). I have spent all my scientific life in Statistics: I have a BSc in Statistics; I am graduated with a MSc degree in Mathematical Statistics from Iran, and I got my PhD in Statistics in Italy.
My main research interests are robust standard errors in generalised linear models and generalised mixed-effect models, and more broadly, statistical inference problems. I have made some new interest on statistical inferences by p-values to modify it to be more rational and less misleading. In addition, I work on improving machine learning algorithms in generic statistical point of view which broadly is known as classification problems, with a focus on human data. I have extensive experience in designing statistical analysis for studies in public health and social care including clinical trials and co-designing research studies to develop health interventions. I have been sitting in National Institute for Health and Care Research (NIHR) MedConnect North and Research Design Service (RDS) panels to provides specialist advise for MedTech industries and research studies.
I am accepting new potential PhD students as “PhD studentship”, please get in touch if you are interested, and we plan for a research proposal together to get it funded to cover the PhD studentship.
Interests and expertise
- Statistical Inference
- Linear and generalised linear models
- Mixed effect models
- Novel Machine Learning
Projects
- 2022 Funder NIHR RfPB: Feasibility and acceptability of a remote exercise and lifestyle change intervention to promote health benefits in patients with smaller abdominal aortic aneurysms. £235,024. (Co-I)
- 2022 Funder NIHR RfPB: Managing Unusual Sensory Experiences (MUSE): A feasibility trial of a targeted, psychoeducation toolkit for distressing hallucinations for people with an At Risk Mental State (ARMS) for psychosis. £249,841. (Co-I)
- 2018 Funder NIHR HTA: A clinical and cost-effectiveness trial of a parent group intervention to manage challenging restricted and repetitive behaviours in young children with autism spectrum disorder (MRB). £1,266,573. (Statistician)
- 2021 Funder NIHR PhR: Adapted suicide safety plans to address self-harm, suicidal ideation and suicide behaviours in autistic adults: an interventional single arm feasibility trial and external pilot randomised controlled trial (AASP). £645,510. (Statistician)
- 2018 Funder NIHR: Research Design Service North East and North Cumbria Region (RDS-NENC). £5,117,229. (Statistician)
- 2021 Funder KANCERA: A phase IIa, randomized, 2-arm parallel-group, placebo-controlled, double-blind, multi- centre trial: RACTalkine inhibition in Acute myocardial infarction (FRACTAL). £1.66m. (Statistician)
- 2018 Funder T.A. Sciences: Telomerase ACTivator to reverse Immunoscenescence in Coronary Artery Disease (TACTIC). £815k (US $1m). (Statistician)
- 2018 Funder NIHR HTA: Multicentre randomised controlled trial of minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for Mitral valve repair (UK Mini Mitral). £1,513,690. (Statistician)
- 2019 Funder NIHR RfPB: Performance characteristics of PillCam Crohn’s compared with conventional ileocolonoscopy and Magnetic Resonance Enterography in the assessment of patients with Crohn’s disease. £249,944. (Statistician)
Research outputs
Surname as Kharatikoopaei:
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=ehsan+kharatikoopaei&btnG=
Surname as Kharati Koopaei:
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=ehsan+kharati+koopaei&btnG=
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Journal articles
Bawamia, B., Spray, L., Wangsaputra, V.K., Bennaceur, K., Vahabi, S., Stellos, K., Kharatikoopaei, E., Ogundimu, E., Gale, C.P., Keavney, B., Maier, R., Hancock, H., Richardson, G., Austin, D., Spyridopoulos, I. (2023) 'Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction.' GeroScience, 45(4) pp. 2689-2705.
Hamilton, J., Arnott, B., Aynsworth, C., Barclay, N.A., Birkett, L., Brandon, T., Dixon, L., Dudley, R., Einbeck, J., Gibbs, C., Kharatikoopaei, E., Simpson, J., Dodgson, G., Fernyhough, C. (2023) 'Use of a targeted, computer/web-based guided self-help psychoeducation toolkit for distressing hallucinations (MUSE) in people with an at-risk mental state for psychosis: protocol for a randomised controlled feasibility trial.' BMJ Open, 13(6)
Akowuah, E.F., Maier, R.H., Hancock, H.C., Kharatikoopaei, E., Vale, L., Fernandez-Garcia, C., Ogundimu, E., Wagnild, J., Mathias, A., Walmsley, Z., Howe, N., Kasim, A., Graham, R., Murphy, G.J., Zacharias, J., Kendall, S., Goodwin, A., Walker, A., Laskawski, G., Modi, P., Pullan, M., Pousios, D., Muir, A., Casula, R., Punjabi, P., Vohra, H., Caputo, M., Ciulli, F., Stoica, S., Zamvar, V., Pessotto, R., Deshpande, R., Wendler, O., Baghai, M., Lloyd, C., Dalrympole-Hay, M., Unsworth-White, J., Bahrami, T., Bhudia, S., De Robertis, F., Rogers, L., Kirmani, B., Abdelrahman, A., O'Rourke, S., Birdi, I., Bhusari, S., Khan, H. (2023) 'Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair: A Randomized Clinical Trial.' JAMA, 329(22) pp. 1957-1966.
Grahame, V., Dixon, L., Fletcher-Watson, S., Garland, D., Glod, M., Goodwin, J., Grayson, Z., Heron, S., Honey, E., Iversen, R., Kasim, A.S., Kernohan, A., Kharatikoopaei, E., Le Couteur, A., Mackie, L., Mathias, A., Probert, H., Riby, D., Rob, P., Rogan, L., Thompson, S., Vale, L., Walls, E., Webb, E.I., Weetman, C., Wolstenhulme, F., Wood, R., Rodgers, J. (2023) 'A clinical and cost-effectiveness trial of a parent group intervention to manage challenging restricted and repetitive behaviours in young children with autism spectrum disorder: study protocol for a randomised controlled trial.' Trials, 22(1) pp. 240-240.
Rodgers, J., Goodwin, J., Nielsen, E., Bhattarai, N., Heslop, P., Kharatikoopaei, E., O’Connor, R.C., Ogundimu, E., Ramsay, S.E., Steele, K., Townsend, E., Vale, L., Walton, E., Wilson, C., Cassidy, S. (2023) 'Adapted suicide safety plans to address self-harm, suicidal ideation, and suicide behaviours in autistic adults: protocol for a pilot randomised controlled trial.' Pilot and Feasibility Studies, 9(1) pp. 31-31.
Dudley, R., Dodgson, G., Common, S., O’Grady, L., Watson, F., Gibbs, C., Arnott, B., Fernyhough, C., Alderson-Day, B., Ogundimu, E., Kharatikoopaei, E., Patton, V., Aynsworth, C. (2022) 'Managing Unusual Sensory Experiences in People with First-Episode Psychosis (MUSE FEP): a study protocol for a single-blind parallel-group randomised controlled feasibility trial.' BMJ Open, 12(5) pp. e061827-e061827.
Kharrati-Kopaei, M., Kharati Koopaei, E. (2018) 'A note on the multiple comparisons of exponential location parameters with several controls under heteroscedasticity.' Hacettepe Journal of Mathematics and Statistics, 47(2) pp. 447-461.
Congedo, M., Barachant, A., Koopaei, E.K. (2017) 'Fixed point algorithms for estimating power means of positive definite matrices.' IEEE Transactions on Signal Processing, 65(9) pp. 2211-2220.