Dr Ayman Mahmoud

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Dr Ayman Mahmoud

Senior Lecturer

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Biography

  • BSc Zoology & Chemistry
  • Diploma Analytical Biochemistry
  • MSc Physiology
  • PhD Physiology

Dr. Mahmoud joined the Department of Life Sciences as a senior lecturer in Cellular & Molecular Physiology. He received his PhD in Physiology from Beni-Suef university (Egypt), where he studied the antidiabetic mechanism of citrus flavonoids and started his lecturer position at the same university. As a winner of the Erasmus Mundus postdoctoral fellowship award, Dr. Mahmoud joined the Department of Pharmacology, Faculty of Pharmacy, Granada University (Spain) to start investigating the role of PPARβ in endothelial function. He received the International Atherosclerosis Society (IAS, USA) 6-month fellowship and the 4-month STDF (Egypt) fellowship awards and spent 10 months working with Prof. Yvonne Alexander (MMU) on exploring the role of microparticles in endothelial function/dysfunction, and the protective potential of a novel class of small molecule glycomimetics against endothelial dysfunction and smooth muscle calcification and his work enabled MMU to take out a patent application. During his short visit to MMU, Dr. Mahmoud won the prestigious Alexander von Humboldt Foundation fellowship award and joined the Center for Cardiovascular Research at Charité – Universitätsmedizin Berlin (Germany) for 2 years. His work focused on studying (a) the role of IGF binding proteins in glucose uptake in adipocytes and endothelial function, (b) the effect of glucagon on IGF-1 bioactivity in humans, and (c) the insulin-sensitizing effect of small molecule glycomimetics. Upon completing this fellowship, Dr. Mahmoud joined the Institute of Diabetes & Obesity at Helmholtz Zentrum München (Germany) as a senior postdoc. He developed a highly specific DNA aptamer targeting thermogenic adipocytes. In December 2019, he started his associate professor position in Cellular & Molecular Physiology in Egypt. Dr. Mahmoud’s research interests focus on pathophysiological mechanisms and novel therapeutic targets for disease, including diabetes, obesity, cardiovascular disease, and drug/chemical-induced toxicity.

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E225 John Dalton Building

Research outputs

CHAPTERS IN BOOKS

  1. Mahmoud AM*. 18. Tramadol as an analgesic, in: R. Rajendram, V. Patel, S. Preedy (Eds.), The Neuroscience of Pain, Anesthetics, and Analgesics, Elsevier Academic Press 2022, pp. Pages 181-191.
  2. Mahmoud AM*, Bin-Jumah M, Abukhalil MA. 9 - Antiinflammatory natural products from marine algae, in: S. Gopi, A. Amalraj, A. Kunnumakkara, S. Thomas (Eds.), Inflammation and Natural Products, Academic Press 2021, pp. 175-203.
  3. Mahmoud AM*. Exercise ameliorates metabolic disturbances and oxidative stress in diabeticcardiomyopathy: possible underlying mechanisms. In: Xiao J. (eds) Exercise for Cardiovascular Disease Prevention and Treatment. Advances in Experimental Medicine and Biology, vol 999. Springer, 2017, p.p. 207-230.
  4. Mahmoud AM*, Hassnien EM. Chapter 17: Ferula asafetida. In Herbs, Spices and Their Roles in Nutraceuticals and Functional Foods. 1st Ed., Elsevier.

JOURNAL ARTICLES

  1. Mahmoud AM*, Sayed AM, Ahmed OS, Abdel-Daim MM, Hassanein EHM. The Role of Flavonoids in Inhibiting IL-6 and Inflammatory Arthritis. Current Topics in Medicinal Chemistry, 2022;22(9):746-768.
  2. Mohamed AE, Mahmoud AM*, Mohamed WR, Mohamed T. Femtosecond laser attenuates oxidative stress, inflammation, and liver fibrosis in rats: Possible role of PPARγ and Nrf2/HO-1 signaling. Life Sciences, 2022 Aug 10:120877. doi: 10.1016/j.lfs.2022.120877.
  3. Alhusaini A, Sarawi W, Mattar D, Abo-Hamad A, Almogren R, Alhumaidan S, Alsultan E, Alsaif S, Hasan I, Hassanein E, Mahmoud A*. Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RARα signaling in rats. Biomedicine & Pharmacotherapy, 2022;153:113360.
  4. Arafa EG, Sabaa MW, Mohamed RR, KameL EM, Abdel-Gawad OF, Mahmoud AM*. Eco-friendly and biodegradable sodium alginate/quaternized chitosan hydrogel for controlled release of urea and its antimicrobial activity. Carbohydrate Polymers, 2022;291: 119555.
  5. Al-Amarat W, Abukhalil MH, Alruhaimi RS, Alqhtani HA, Aldawood N, Alfwuaires MA, Althunibat OY, Aladaileh SH, Algefare AI, Alanezi AA, AbouEl-Ezz AM, Ahmeda AF, Mahmoud AM*. Upregulation of Nrf2/HO-1 Signaling and Attenuation of Oxidative Stress, Inflammation, and Cell Death Mediate the Protective Effect of Apigenin against Cyclophosphamide Hepatotoxicity. Metabolites, 2022;12(7):648.
  6. Ajarem JS, Hegazy AK, Allam GA, Allam AA, Maodaa SN, Mahmoud AM*. Impact of petroleum industry on goats in Saudi Arabia: heavy metal accumulation, oxidative stress, and tissue injury. Environmental Science and Pollution Research, 2022. doi: 10.1007/s11356-022-22309-0.
  7. Sarawi WS, Alhusaini AM, Fadda LM, Alomar HA, Albaker AB, Alghibiwi HK, Aljrboa AS, Alotaibi AM, Hasan IH, Mahmoud AM*. Nano-Curcumin Prevents Copper Reproductive Toxicity by Attenuating Oxidative Stress and Inflammation and Improving Nrf2/HO-1 Signaling and Pituitary-Gonadal Axis in Male Rats. Toxics, 2022;10(7):356.
  8. Saghir SAM, Abdulghani MAM, Alruhaimi RS, Ahmeda AF, Al-Gabri NA, Alomaisi SAMA, Sadikun A, Murugaiyah V, Mahmoud AM*. Acute and sub-chronic toxicological evaluation of Averrhoa carambola leaves in Sprague Dawley rats. Environmental Science and Pollution Research, 2022. doi: 10.1007/s11356-022-22019-7.
  9. El-Bab AFF, Saghir SAM, El-Naser IAA, El-Kheir SMMA, Abdel-Kader MF, Alruhaimi RS, Alqhtani HA, Mahmoud AM, Naiel MAE, El-Raghi AA. The Effect of Dietary Saccharomyces cerevisiae on Growth Performance, Oxidative Status, and Immune Response of Sea Bream (Sparus aurata). Life (Basel), 2022;12(7):1013.
  10. Althunibat OY, Abduh MS, Abukhalil MH, Aladaileh SH, Hanieh H, Mahmoud AM*. Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats. Biomedicine & Pharmacotherapy, 2022;149:112900.
  11. Alshawsh MA, [], Mahmoud AM. A Comparison of the Gene Expression Profiles of Non-Alcoholic Fatty Liver Disease between Animal Models of a High-Fat Diet and Methionine-Choline-Deficient Diet. Molecules. 2022;27(3):858.
  12. Allam MA, [], Mahmoud AM*. Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates PPARγ in type 2 diabetic rats. Journal of Pharmacy and Pharmacology, 2022;74(4):573-584.
  13. Arab H, Abd El-Aal S, Ashour A, El-Sheikh A, Al Khabbaz H, Arafa E, Mahmoud AM, Kabel A. Targeting inflammation and redox perturbations by lisinopril mitigates Freund’s adjuvant-induced arthritis in rats. Inflammopharmacology, 2022. doi: 10.1007/s10787-022-00998-w.
  14. Atiba A, Abdo W, Ali E, Abd-Elsalam M, Amer M, Abdel Monsef A, Taha R, Antar S, Mahmoud A*. Topical and oral applications of Aloe vera improve healing of deep second-degree burns in rats via modulation of growth factors. Biomarkers, 2022. doi: 10.1080/1354750X.2022.2085800.
  15. Kamel EM, Ahmed NA, El-Bassuony AA, Hussein OE, Alrashdi B, Ahmed SA, Lamsabhi AM, Arab HH, Mahmoud AM*. Xanthine Oxidase Inhibitory Activity of Euphorbia peplus L. Phenolics. Combinatorial Chemistry & High Throughput Screening, 2022;25(8):1336-1344.
  16. Refay SM, Ahmed EH, Abd ELzaher AR, Morsy AM, Yasser MM, Mahmoud AM*. Risk of Drug Resistance and Repeated Infection with Klebsiella pneumoniae and Escherichia coli in Intensive Care Unit Cancer Patients. Combinatorial Chemistry & High Throughput Screening, 2022;25(2):324-334.
  17. ALRashdi BM, Elgebaly H, Germoush MO, [], Mahmoud AM*. A flavonoid-rich fraction of Monolluma quadrangula inhibits xanthine oxidase and ameliorates potassium oxonate-induced hyperuricemia in rats. Environmental Science and Pollution Research, 2022; doi: 10.1007/s11356-022-20274-2.
  18. Ajarem JS, Hegazy AK, Allam GA, Allam AA, Maodaa SN, Mahmoud AM*. Heavy Metal Accumulation, Tissue Injury, Oxidative Stress, and Inflammation in Dromedary Camels Living near Petroleum Industry Sites in Saudi Arabia. Animals, 2022; 12(6):707.
  19. Elshemy HAH, Zaki MA, Mahmoud AM, Khan SI, Chittiboyina AG, Kamal AM. Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism. Bioorganic Chemistry, 2022;118:105475.
  20. Antar S, [], Mahmoud AM*. Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats. Life Sciences, 2022; LFS_120260.
  21. Arab HH, [], Mahmoud AM, Ashour AM. Targeting inflammation, autophagy, and apoptosis by troxerutin attenuates methotrexate-induced renal injury in rats. International Immunopharmacology, 2022;103: 108284.
  22. Mahmoud AM*, Wilkinson F, Sandhu M, Lightfoot A. The Interplay of Oxidative Stress and Inflammation: Mechanistic Insights and Therapeutic Potential of Antioxidants. Oxidative Medicine & Cellular Longevity, 2021;2021:9851914.
  23. Mahmoud AM*, [], Hassanein EM. Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1. Life Sciences, 2021;278:119600.
  24. Sarawi WS, [], Mahmoud AM*. Nano-Curcumin Prevents Cardiac Injury, Oxidative Stress and Inflammation, and Modulates TLR4/NF-κB and MAPK Signaling in Copper Sulfate-Intoxicated Rats. Antioxidants, 2021;10:1414.
  25. Sarawi WS, [], Mahmoud AM*. Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling. Molecules, 2021;26:5591.
  26. Abd El-Ghafar O, [], Mahmoud AM*. Acetovanillone prevents cyclophosphamide-induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats. Phytotherapy Research, 2021;35:4499-4510.
  27. Hassanein EM, [], Mahmoud AM*. Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR-4/NF-κB, and JAK1/STAT3 signaling in cyclophosphamide-intoxicated rats. Journal of Biochemical and Molecular Toxicology 2021;35(11):e22889.
  28. Abd Allah HN, Abdul-Hamid M, Mahmoud AM*, Abdel-Reheim ES. Melissa officinalis L. ameliorates oxidative stress and inflammation and upregulates Nrf2/HO-1 signaling in the hippocampus of pilocarpine-induced rats. Environmental Science & Pollution Research, 2021;29(2):2214-2226.
  29. Abukhalil M, [], Mahmoud AM*. Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation, and upregulating Nrf2 signaling in rats. Journal of Biochemical and Molecular Toxicology 2021;35(11):e22906.
  30. Al-Amarat W, [], Mahmoud AM*.  Galangin attenuates liver injury, oxidative stress and inflammation, and upregulates Nrf2/HO-1 signaling in streptozotocin-induced diabetic rats. Processes, 2021; 9(9);1562.
  31. Aladaileh SH, [], Mahmoud AM*. Punicalagin prevents cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammatory response, and apoptosis in rats. Life Sciences, 2021;286:120071.
  32. Arab HH, [], Mahmoud AM, Kabel A. Activation of AMPK/mTOR-driven autophagy and inhibition of NLRP3 inflammasome by saxagliptin ameliorate ethanol-induced gastric mucosal damage. Life Sciences, 2021;280:119743.
  33. Ajarem J, [], Mahmoud AM*. Anethum graveolens prevents liver and kidney injury, oxidative stress and inflammation in mice exposed to nicotine perinatally. Coatings, 2021:11(6):621.
  34. Saghir S, [], Mahmoud AM*. Ameliorative Effect of Thymoquinone-Loaded PLGA Nanoparticles on Chronic Lung Injury Induced by Repetitive Intratracheal Instillation of Lipopolysaccharide in Rats. Oxidative Medicine & Cellular Longevity, 2021;2021: 5511523.
  35. Arab HH, Eid AH, Mahmoud AM, Senousy MA. Linagliptin mitigates experimental inflammatory bowel disease in rats by targeting inflammatory and redox signaling. Life Sciences, 2021;273:119295.
  36. Gill DM, [], Mahmoud AM, [], Cornelio ML, Jones AM. The modulatory role of sulfated and non-sulfated small molecule heparin-glycomimetics in endothelial dysfunction: Absolute structural revision, molecular docking and simulated dynamics, SAR analyses and ADME studies. RSC Medicinal Chemistry, 2021;12: 779-790.
  37. Ajarem JS, [], Mahmoud AM*. Effect of visnagin on altered steroidogenesis and spermatogenesis, and testicular injury induced by the heavy metal lead. Combinatorial Chemistry & High Throughput Screening, 2021;24(6):758-766.
  38. Ranneh Y, Mahmoud AM*, Fadel A, Albujja M, Akim AM, Hamid HA, Khazaai H. Acute Inflammation and Oxidative Stress Induced by Lipopolysaccharide and the Ameliorative Effect of Stingless Bee Honey. Combinatorial Chemistry & High Throughput Screening, 2021;24(6):744-757.
  39. Arab HH, [], Mahmoud AM, Kabel A. Inhibition of oxidative stress and apoptosis by camel milk mitigates cyclosporine‐induced nephrotoxicity: Targeting Nrf2/HO‐1 and AKT/eNOS/NO pathways. Food Science & Nutrition, 2021;9(6):3177-3190.
  40. Abukhalil MA, [], Mahmoud AM*. Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats. Biomedicine & Pharmacotherapy, 2021;138:111410.
  41. Mahmoud AM*, [], Abd El-Twab SM. Ferulic acid prevents oxidative stress, inflammation and liver injury via up-regulation of Nrf2/HO-1 signaling in methotrexate-induced rats. Environmental Science & Pollution Research, 2020; 27:7910–7921.
  42. Germoush MO, [], Mahmoud AM*. Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes. Antioxidants, 2020; 9:22.
  43. Al-Basher G, [], Mahmoud AM*. Perinatal exposure to tartrazine triggers oxidative stress and neurobehavioral alterations in mice offspring. Antioxidants, 2020; 9:53.
  44. Hassanein EM, [], Mahmoud AM*. Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2020; 2020; 1675957.
  45. Hassanein EM, [], Mahmoud AM*. Edaravone and Acetovanillone Upregulate Nrf2 and PI3K/Akt/mTOR Signaling and Prevent Cyclophosphamide Cardiotoxicity in Rats. Drug Design, Development and Therapy 2020; 14:5275-5288.
  46. Alanazi AM, [], Mahmoud AM*. Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats. Antioxidants, 2020; 9:159.
  47. Tahoun A, [], Mahmoud AM*. Inflammasome activation in bovine peripheral blood-derived macrophages is associated with actin rearrangement. Animals, 2020;10:655.
  48. Elsayed RH, Kamel EM, Mahmoud AM*, [], Ahmed SA. Rumex dentatus L. phenolics ameliorate hyperglycemia by modulating hepatic key enzymes of carbohydrate metabolism, oxidative stress and PPARγ in diabetic rats. Food & Chemical Toxicology, 2020; 138:111202.
  49.  Hussein OE, [], Mahmoud AM*. Chicoric acid prevents methotrexate hepatotoxicity via attenuation of oxidative stress and inflammation and up-regulation of PPARγ and Nrf2/HO-1 signaling. Environmental Science & Pollution Research, 2020; 27(17):20725-20735.
  50. Taha GM, [], Mahmoud AM*. Metabolomic profiling and antioxidant, anticancer and antimicrobial activities of Hyphaene thebaica. Processes, 2020;8:266.
  51. El-Malky, [], Mahmoud AM*. Use of Spilopelia senegalensis as a biomonitor of heavy metals contamination from mining activities in Riyadh (Saudi Arabia). Animals, 2020;9:1046.
  52. Ismaeil H, [], Mahmoud AM*. Ameliorative Effect of Heat-Killed Lactobacillus plantarum L.137 and/or Aloe vera against Colitis in Mice. Processes, 2020;8:225.
  53. Saghir SAM, [], Mahmoud AM*. Curcumin Prevents Cyclophosphamide-Induced Lung Injury in Rats by Suppressing Oxidative Stress and Apoptosis. Processes, 2020;8:127.
  54. Abukhalil MA, [], Mahmoud AM*. Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats. Environmental Science & Pollution Research, 2020; 27(24):30118-30132.
  55. Alotaibi MF, [], Mahmoud AM*. Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling. Drug Design, Development & Therapy, 2020; 14: 4003-4019.
  56. Khadrawy SM, [], Mahmoud AM*. Mesenchymal stem cells ameliorate oxidative stress, inflammation, and hepatic fibrosis via Nrf2/HO-1 signaling pathway in rats. Environmental Science & Pollution Research, 2020; 28(2):2019-2030.
  57. Sayed A, [], Mahmoud AM*. Flavonoids-mediated SIRT1 signaling activation in hepatic disorders. Life Sciences, 2020: 118173.
  58. Othman S, [], Mahmoud AM*. Camel Urine Prevents Cisplatin-induced Nephrotoxicity in Rats by Attenuating Oxidative Stress and Apoptosis. International Journal of Pharmacology, 2020; 16(3):257-266.
  59. Elgebaly H, [], Mahmoud AM*. Adenium obesum Flowers Extract Mitigates Testicular Injury and Oxidative Stress in Streptozotocin-induced Diabetic Rats. International Journal of Pharmacology, 2020; 16(4): 310-318.
  60. Al-dossary M, [], Mahmoud AM*. Curcumin and selenium prevent lipopolysaccharide/diclofenac-induced liver injury by suppressing inflammation and oxidative stress. Biological Trace Element Research, 2020; 196: 173–183.
  61. El-Sharkawy H, [], Mahmoud AM*. Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens. Animals, 2020;10(6):1023.
  62. Abo Ghanima M, [], Mahmoud AM. Consequences of various housing systems and dietary supplementation of thymol, carvacrol and euganol on performance, egg quality, blood chemistry and antioxidant parameters. Poultry Science, 2020; 99: 4384-4397.
  63. Al Hroob A, [], Mahmoud AM. Prevalence and Association of Transfusion Transmitted Infections with ABO and Rh Blood Groups among Blood Donors at the National Blood Bank, Amman, Jordan. Medicina, 2020; 56: 701.
  64. Mahmoud AM*, [], Hussein OM. Citrus Flavonoids in Cardiovascular and Metabolic Health. Oxidative Medicine & Cellular Longevity, 2019; 2019: 5484138.
  65. Mahmoud AM*, [], Alexander MY. Modulating Oxidative Stress in Drug-Induced Injury and Metabolic Disorders: The Role of Natural and Synthetic Antioxidants. Oxidative Medicine & Cellular Longevity, 2019; 2019: 3206401.
  66. Mahmoud AM*, [], Shaban E. Umbelliferone ameliorates CCl4-induced liver fibrosis in rats by up- regulating PPARγ and attenuating oxidative stress, inflammation and TGF-β1/Smad3 signaling. Inflammation, 2019;42(3):1103-1116.
  67. Mahmoud AM*, Hozayen, WG, [], Farghali AA. Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats. Biomedicine & Pharmacotherapy, 2019; 109:2527-2538. AMM & WGH participated as first author
  68. Mahmoud AM*, [], Hozayen WG. Ferulic acid protects against methotrexate nephrotoxicity via activation of Nrf2/ARE/HO-1 signaling and PPARγ, and suppression of NF-κB/NLRP3 inflammasome axis. Food & Function, 2019;10(8):4593-4607.
  69. Mahmoud AM, [], Alexander MY. Small molecule glycomimetics inhibit vascular calcification via c- Met/Notch3/HES1 signalling. Cellular Physiology & Biochemistry, 2019;53(2):323-336.
  70. Mahmoud AM*, [], Farghali AA. Mesoporous silica nanoparticles trigger liver and kidney injury and fibrosis via altering TLR4/NF-κB, JAK2/STAT3 and Nrf2/HO-1 signaling in rats. Biomolecules, 2019; 9 (10): 528.
  71. Al-Basher G, [], Mahmoud AM*. Ameliorative effect of Beta vulgaris root extract on chlorpyrifos-induced oxidative stress, inflammation and liver injury in rats. Biomolecules, 2019; 9(7): 261.
  72. Aladaileh S, [], Mahmoud AM*. Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity. Biomolecules, 2019; 9(8):346.
  73. Aladaileh S, [], Mahmoud AM*. Formononetin upregulates Nrf2/HO-1 signaling and prevents oxidative stress, inflammation, and kidney injury in methotrexate-induced rats. Antioxidants, 2019; 8 (10): 430.
  74. Abd El-Twab SM, [], Mahmoud AM*. Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling. Inflammation Research, 2019; 68(6):511-523.
  75. Al-Basher G, [], Mahmoud AM*. Chronic exposure to 35% carbamide peroxide tooth bleaching agent induces histological and hematological alterations, oxidative stress, and inflammation in mice. Environmental Science and Pollution Research, 2019; 26(17):17427-17437.
  76. Althunibat OY, [], Mahmoud AM*. Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy. Life Sciences, 2019;221:83-92.
  77. Ranneh Y, [], Mahmoud AM. Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK. Nutrition & Metabolism, 2019; 16:15.
  78. Hernández Bautista, Mahmoud AM, Konigsberg M, López Díaz Guerrero N. Obesity: Pathophysiology, monosodium glutamate-induced model and anti-obesity medicinal plants. Biomedicine & Pharmacotherapy, 2019;111:503-516.
  79. Mohamed HM, Mahmoud AM*. Chronic exposure to the opioid tramadol induces oxidative damage, inflammation and apoptosis, and alters cerebral monoamine neurotransmitters in rats. Biomedicine & Pharmacotherapy, 2019; 110:239-247.
  80. Allam A, [], Mahmoud AM*. Deleterious effects of perinatal exposure to potassium bromate on the development of offspring of Swiss mice. Toxicology and Industrial Health, 2019;35(1): 63-78.
  81. Al Hroob AM, [], Mahmoud AM*. Pathophysiological mechanisms of diabetic cardiomyopathy and the therapeutic potential of epigallocatechin-3-gallate. Biomedicine & Pharmacotherapy. 2019; 109:2155-2172.
  82. ALHaithloul H, [], Mahmoud AM*. Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney. Biomedicine & Pharmacotherapy, 2019;111:676-685.
  83. El-massry K, [], Mahmoud AM*. Microencapsulation of date seed oil by spray-drying for stabilization of olive oil as a functional food. Asian Journal of Scientific Research, 2019;12(4):516-523.
  84. El-Malky AM, [], Mahmoud AM*. Effects of Mining Activities on Gerbillus nanus in Saudi Arabia: A Biochemical and Histological Study. Animals, 2019;9(9):664.
  85. Alhusaini A, [], Mahmoud AM*. Curcumin ameliorates lead-induced hepatotoxicity by suppressing oxidative stress and inflammation, and modulating Akt/GSK-3β signaling pathway. Biomolecules, 2019;9:703.
  86. Alhusaini A, [], Mahmoud AM*. Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3β Signaling. Antioxidants, 2019;8:582.
  87. Aladaileh S, [], Mahmoud AM, Murugaiyah V, Antihyperlipidemic and antioxidant effects of Averrhoa carambola extract in high fat diet-fed rats. Biomedicines, 2019: 7(3): 72.
  88. Mahmoud AM*, [], Allam. AA.Commiphora molmolprotects against methotrexate-induced nephrotoxicityby up-regulating Nrf2/ARE/HO-1 signaling. Biomed Pharmacother. 2018; 106:499-509.
  89. Mahmoud AM*, Fadel A, Ashworth JJ, Li W, Ng YL, Plunkett A. Health-related effects and improvingextractability of cereal arabinoxylans. Int J Biol Macromol. 2018; 109:819-831. AMM & AF participated as first author
  90. Al Hroob AM, [], Mahmoud AM*. Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy. Biomed Pharmacother. 2018; 106: 381-389.
  91. Fadel A, [], Mahmoud AM, Weili Li. Improving the extractability of arabinoxylans and the molecular weight of wheat endosperm using extrusion processing. Journal of Cereal Science, 2018;84:55-61.
  92. Al-Otaibi F, Ajarem J, [], Mahmoud AM*. Stone quarrying induces organ dysfunction and oxidative stress in Meriones libycus. Toxicology and Industrial Health. Toxicol Ind Health. 2018; 34(10):679-692.
  93. Al-Rasheed NM, [], Mahmoud AM*. Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes. Biomed Pharmacother. 2018;105:290-298.
  94. Germoush MO, [], Mahmoud AM*. Umbelliferone prevents oxidative stress, inflammation and hematological alterations, and modulates glutamate-nitric oxide-cGMP signaling in hyperammonemic rats. Biomed Pharmacother. 2018;102:392-402.
  95. Elgebaly HA, Mosa NM, […], Mahmoud AM*. Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis. Biomed Pharmacother. 2018;98:446-453.
  96. Fadel A, […], Mahmoud AM, Ranneh Y, Ashworth J, Li W. The effect of extrusion screw-speed on the water extractability and molecular weight distribution of Arabinoxylans from defatted rice bran. J Food Sci Technol., 2018; 55: 1201–1206.
  97. Albshr GI, [], Mahmoud AM*. Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain, and behavioral alterations in mice offspring. Biomed Pharmacother. 2018;102:798-811.
  98. Ahmed OM, Fahim H, Mahmoud AM, Ahmed E. Bee venom and hesperidin effectively mitigate complete Freund’s adjuvant-induced arthritis via immunomodulation and enhancement of antioxidant defense system. Arch Rheumatol 2018; 33(2):770-785.
  99. Mahmoud AM, […], M. Yvonne Alexander. Endothelial microparticles prevent lipid-induced endothelialdamage via Akt/eNOS signaling and reduced oxidative stress. FASEB J, 2017; 31(10):4636-4648.
  100. Mahmoud AM,[…], Alexander MY. A novel role for small molecule glycomimetics in the protection againstlipid-induced endothelial dysfunction: involvement of Akt/eNOS and Nrf2/ARE signaling. Biochim Biophys Acta. 2017;1861:3311-22.
  101. Mahmoud AM*, […], Allam AA.Commiphora molmolmodulates glutamate-nitric oxide-cGMP andNrf2/ARE/HO-1 pathways and attenuates oxidative stress and hematological alterations in hyperammonemic rats. Oxidative Medicine and Cellular Longevity, 2017;2017:7369671.
  102. Mahmoud AM*, Abd El-Twab SM, Abdel-Reheim ES. Consumption of polyphenol-richMorus albaleavesextract attenuates early diabetic retinopathy: the underlying mechanism. European Journal of Nutrition, 2017;56:1671-84.
  103. Mahmoud AM*, Abd El-Twab SM. Caffeic acid phenethyl ester protects the brain against chromium toxicityby enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway. Biomedicine & Pharmacotherapy, 2017;91:303-11.
  104. Mahmoud AM*, Mohamed HM, Khadrawy SM, Galaly SR. Hesperidin protects against chemically inducedhepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation. Chemico-Biological Interactions, 2017;277:146-158.
  105. Mahmoud AM*, Hussein OE, Hozayen WG, Abd El-Twab SM. Methotrexate hepatotoxicity is associatedwith oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid. Chemico-Biological Interactions, 2017;270:59-72.
  106. Mahmoud AM*, Hozayen WG, Ramadan SM. Berberine ameliorates methotrexate-induced liver injury byactivating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats. Biomedicine & Pharmacotherapy, 2017; 94:280-91.
  107. Mahmoud AM*, Zaki AR, Hassan ME, Mostafa-Hedeab G.Commiphora molmolresin attenuatesdiethylnitrosamine/phenobarbital-induced hepatocarcinogenesis by modulating oxidative stress, inflammation, angiogenesis and Nrf2/ARE/HO-1 signaling. Chemico-Biological Interactions,  2017;270:41-50.
  108. Mahmoud AM*, Germoush MO, Alotaibi MF, Hussein OE. Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity. Biomedicine & Pharmacotherapy, 2017;86:297-306.
  109. Assefa B, Mahmoud AM, […], Arafat AM. Insulin-like growth factor (IGF) binding protein-2, independently of IGF-1, induces GLUT-4 translocation and glucose uptake in 3T3-L1 adipocytes. Oxidative Medicine and Cellular Longevity, 2017;2017:3035184.
  110. Mahmoud AM*, Alexander MY, Tutar Y, Wilkinson FL, Venditti, A. Oxidative Stress in MetabolicDisorders and Drug-Induced Injury: The Potential Role of Nrf2 and PPARs Activators. Oxidative Medicine and Cellular Longevity, 2017;2017:2508909.
  111. Aly MS, […], Mahmoud AM*. Hesperidin protects against diethylnitrosamine/carbon tetrachloride-induced renal repercussions via up-regulation of Nrf2/HO-1 signaling and attenuation of oxidative stress. Journal of Applied Pharmaceutical Science, 2017; 7 (11): 007-014.
  112. Hozayen WG, Ramadan SM, Fadel A, Mahmoud AM*. Berberine mitigates methotrexate-induced oxidative stress and inflammation in the cerebrum of rats. Journal of Applied Pharmaceutical Science, 2017; 7 (11): 043-049.
  113. Mahmoud AM*, Abdel-Rahman MM, Bastawy NA, Eisa HM. Modulatory effect of berberine on adiposetissue PPARγ, adipocytokines and oxidative stress in high fat diet/streptozotocin-induced diabetic rats. Journal of Applied Pharmaceutical Science, 2017;7(4):1-10.
  114. Mahmoud AM, Satta S, […], White S. The role of Nrf2 in Cardiovascular Function and Disease. Oxidative Medicine and Cellular Longevity, 2017;2017:9237263. AMM & SS participated as first author.
  115. Al-Basher G, […], Mahmoud AM*. Green tea protects against perinatal nicotine-induced histological, biochemical and hematological alterations in mice offspring. International Journal of Pharmacology, 2017;13:109-21.
  116. Hamed AI, […], Mahmoud AM, Elgebaly HA, Perez AJ, Stochmal A. Fingerprinting of Strong Spermatogenesis Steroidal Saponins in Male Flowers of Phoenix dactylifera (Date Palm) by LC-ESI-MS. Natural Product Research, 2017;31:2024-31.
  117. Ajarem JS, […], Mahmoud AM*. Camellia sinensis prevents perinatal nicotine-induced neurobehavioral alterations, tissue injury and oxidative stress in male and female mice newborns. Oxidative Medicine and Cellular Longevity, 2017;2017:5985219.
  118. Abdel-Rahman MM, Mahmoud AM*, Bastawy NA, Eisa HM. Anti-hyperlipidemic and myocardial enhancing effects of berberine in high fat diet/streptozotocin-induced diabetic rats; possible role of adiponectin. Nutrutrition and Food Science International Journal, 2017;2(1): 555580.
  119. Al-Rasheed N, […], Mahmoud AM*. Simvastatin ameliorates diabetic cardiomyopathy by attenuating oxidative stress and inflammation in rats. Oxidative Medicine and Cellular Longevity, 2017;2017: 1092015.
  120. Sarem S, Bumke-Vogt C, Mahmoud AM, […], Arafat AM. Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins. Journal of Clinical Endocrinology and Metabolism, 2017;102(9):3480-3490.
  121. Mahmoud AM*, Alqahtani S. Gamma-glutamylcysteine ethyl ester protects against cyclophosphamide-induced liver injury and hematologic alterations via upregulation of PPARγ and attenuation of oxidative stress, inflammation, and apoptosis. Oxidative Medicine and Cellular Longevity, 2016;2016:4016209. Both authors contributed as first author.
  122. Mahmoud AM*, Abdella EM, El-Derby AM. Brown seaweeds protect against azoxymethane-inducedhepatic repercussions through up-regulation of peroxisome proliferator activated receptor gamma and attenuation of oxidative stress. Pharmaceutical Biology, 2016;54:2496-504. Mahmoud AM and Abdella EM contributed as first author.
  123. Mahmoud AM*. Protective effects of umbelliferone in experimental testicular ischaemia/ reperfusion injuryin rats. Anatomy and Physiology, 2016;6:189.
  124. Mahmoud AM*, Hussein OE. Hesperidin as a promising anti-diabetic flavonoid: the underlying molecularmechanism. Int J Food Nutr Sci. 2016;3(3):1-3.
  125. Mahmoud AM*, Hussein OE. Anti-Diabetic Effect of Naringin: Insights into the Molecular Mechanism.Diab Obes Int, 2016;1(5):000128
  126. Mahmoud AM*, Hussein OE. Flavonoids as potential Wnt/β-Catenin signaling modulators for colorectalcancer prevention. Int J Food Nutr Sci. 2016;3(1):1-3.
  127. Kamel EM, Mahmoud AM*, Ahmed SA, Lamsabhi AM. A Phytochemical and computational study on flavonoids isolated from Trifolium resupinatum L. and novel hepatoprotective activity. Food & Function, 2016;7:2094-106.
  128. Mahmoud AM*, Soliman HA, Abd El-Hameed AM, Abd El-Rehim ES. Wheat germ oil attenuatescyclophosphamide-induced testicular injury in rats. World J Pharm Pharm Sci. 2016;5(5):40-52.
  129. Hozayen WG, Mahmoud AM*, Soliman HA, Mostafa SR. Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats. J Intercult Ethnopharmacol. 2016;5(1):57-64.
  130. Abdel-Rahman MM, Mahmoud AM*, Mostafa NM, Saleh ME, Eissa HM. Sildenafil reduces ischemia/reperfusion testicular injury after torsion/detorsion in rats. J Appl Pharm Sci. 2016;6(2):135-40.
  131. Ahmed OM, Mahmoud AM, AbouZid S, Saber NY. Silymarin and hydroethanolic extracts of Silybum marianum leaves and fruits attenuate diethylnitrosamine/phenobarbital-induced nephrotoxicity via their antioxidant and anti-inflammatory actions. Am J Biochem. 2016;6(2):21-29.
  132. Abd El-Twab SM, Mohamed HM, Mahmoud AM*. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary/gonadal axis. Can J Physiol Pharmacol. 2016;94(6):651-661.
  133. Al-Rasheed NM, […], Mahmoud AM*. Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats. Drug Des Devel Ther. 2016;10:2095-107.
  134. Abd El-Twab SM, […], Mahmoud AM*. 18β-Glycyrrhetinic acid protects against methotrexate-induced kidney injury by up-regulating the Nrf2/ARE/HO-1 pathway and endogenous antioxidants. Ren Fail. 2016;38:1516-27.
  135. Abd El-Rehim ES, Mahmoud AM*, Abd El-Hameed AM, Soliman HA. Effect of cinnamaldehyde on the toxicity of cyclophosphamide in the testes of rats: influence of pre- and post-treatment schedule. Nat Sci. 2016;14(5):44-51.
  136. Hussein OE, Germoush MO, Mahmoud AM*. Ruta graveolens protects against isoniazid/rifampicin-induced nephrotoxicity through modulation of oxidative stress and inflammation. Glob J Biotechnol Biomater Sci. 2016;1:17-22.
  137. Al-Samhari MM, […], Mahmoud AM*, Dzimiri N. Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects. Exp Biol Med (Maywood). 2016;241:509-18.
  138. AL-Rasheed NM, […], Mahmoud AM*, Abdel-Twab RM, Yacoub HI. Protective effects of silymarin, alone or in combination with chlorogenic acid and/or melatonin, against carbon tetrachloride-induced hepatotoxicity. Pharmacogn Mag. 2016;12:S337-S45.
  139. Mahmoud AM*, Ahmed OM, Ashour MB, Abdel-Moneim A. In vivo and in vitro antidiabetic effects ofcitrus flavonoids; A study on the mechanism of action. Int J Diabetes Dev Ctries. 2015;35(3):250-63.
  140. Mahmoud AM*, Al Dera HS. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes Nutr. 2015;10(6):41.
  141. Mahmoud AM*, Abdella EM, Abdella EM, El-Derby AM. Protective effects of Turbinaria ornata and Padinapavonia against azoxymethane-induced carcinogenesis through modulation of PPAR gamma, NF-κB and oxidative stress. Phytother Res. 2015;29:737-48.
  142. Mahmoud AM*, Hozayen WG,Soliman HA, Mostafa SR. Enteromorpha flexuosa Improves InsulinSensitivity and Metabolic Control in Fructose-Induced Diabetic Rats. J Endocrinol Diab Obes. 2015;3(2):1072.
  143. Mahmoud AM*, Morsy BM, Abdel-Hady DS, Samy RM.Prunus armeniacaLeave Extract Protects againstIsoniazid and Rifampicin Induced Nephrotoxicity through Modulation of Oxidative stress and Inflammation. Int J Food Nutr Sci. 2015;2(4):1-6.
  144. Mahmoud AM*, Ahmed RR, Soliman HA, Salah M. Ruta graveolens and its active constituent rutin protectagainst diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress. J Appl Pharm Sci. 2015;5(10):16-21. Scopus indexed
  145. Mahmoud AM*. Flavonoids as Ligands for Peroxisome Proliferator-Activated Receptor γ. Int J Food NutrSci.2015;2(4):1-2.
  146. Toral M, Romero M, Jiménez R, Mahmoud AM, […], Duarte J. Carnitine palmitoyl transferase-1 up-regulation by PPAR-β/δ prevents lipid induced endothelial dysfunction. Clin Sci (Lond). 2015;129(9):823-837.
  147. Ahmed RR, Mahmoud AM, […], Ebaid H. Up-regulation of Hsp72 and keratin16 mediates wound healing in streptozotocin diabetic rats. Biol Res. 2015;48:54.
  148. Ahmed RR, Mahmoud AM*, Ashour MB, Kamel AM. Hesperidin protects against diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress and inflammation. Natl J Physiol Pharm Pharmacol. 2015;5(5):391-7.
  149. Soliman HA, Hozayen WG, Mahmoud AM*, Fayed NA, Abo-Seif MA. Significance of the hepatitis C virus core antigen testing as an alternate marker for hepatitis diagnosis in Egyptian patients. Eur Rev Med Pharmacol Sci. 2015;19:2240-5.
  150. Germoush MO, […], Mahmoud AM. Anti-diabetic effects of Padina pavonia in fructose-induced diabetic rats. AUSEJ. 2015;2(2):10-6.
  151. Al-Rasheed NM, […], Mahmoud AM*. Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway. Drug Des Devel Ther. 2015;9:3217-29.
  152. Mahmoud AM*. Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation ofPPARγ and abrogation of oxidative stress and inflammation. Can J Physiol Pharmacol. 2014; 92(91):717-24.
  153. Mahmoud AM*, Germoush MO, Soliman AS. Berberine attenuates isoniazid-induced hepatotoxicity bymodulating peroxisome proliferator-activated receptors γ, oxidative stress and inflammation. Int J Pharmacol. 2014;10:451-60.
  154. Mahmoud AM*, Galaly SR, Ahmed OM. Thymoquinone and curcumin attenuate gentamicin-induced renaloxidative stress, inflammation and apoptosis in rats. EXCLI J. 2014;13:98-110.
  155. Mahmoud AM*, […], Abdella EM. Brown Seaweeds Ameliorate Renal Alterations in Mice Treated with theCarcinogen Azoxymethane. Int J Pharm Pharm Sci. 2014;6:365-9.
  156. Mahmoud AM*, […], Hussein OE. Antidiabetic and insulin sensitizing effects ofPadina pavoniaandTurbenaria ornata in streptozotocin/nicotinamide diabetic rats. Asian J Pharm Clin Res. 2014;7(4):74-78. Scopus indexed
  157. Mahmoud AM*, Germoush MO, Soliman AS.Ruta graveolensmitigates ammonium chloride-inducedhyperammonemia by modulating antioxidant status and pro-inflammatory cytokines. Life Sci J. 2014;11(6):269-275. Scopus indexed
  158. Germoush MO, Mahmoud AM. Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines. J Cancer Res Clin Oncol. 2014;140:1103-9.
  159. Soliman AS, Mahmoud AM*, Serry ZMH, Daood, FG. Therapeutic effects of low-level laser and reflexology on adhesive capsulitis in elderly type 2 diabetic patients. Asian J Pharm Clin Res. 2014;7(5):317-321. Scopus indexed
  160. Morsy BM, Mahmoud AM*, Zanaty MI, Abdel-Moneim A, Abo-Seif MA. Beneficial effects of milk kefir in patients with chronic hepatitis C virus infection. Int J Bioassays, 2014;3:3086-91.
  161. Osman AA, Mahmoud AM*, Soliman AS. Rapid Detection of Bovine-specific Nucleic Acid Sequences in Cow Milk Using Polymerase Chain Reaction. Int J Nutr Food Sci. 2014;3:141-4.
  162. Ahmed OM, […], Mahmoud AM, Ahmed NA. Preventive effect of Spirulina versicolor and Enteromorpha flexuosa ethanolic extracts against diethylnitrosamine/benzo(a)pyrene-induced hepatocarcinogenecity in rats.JIARM, 2014;2(6):633-50.
  163. Galaly SR, Ahmed OM, Mahmoud AM. Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative Stress and inflammation. J Physiol Pharmacol. 2014; 65:823-32.
  164. Abouzid SF, […], Mahmoud AM, Abdella E, Ashour MB. Antihyperglycemic effect of crude extracts of some Egyptian plants and algae. J Med Food. 2014;17:400-406.
  165. Mahmoud AM*. Hematological alterations in diabetic rats - Role of adipocytokines and effect of citrusflavonoids. EXCLI J, 2013;12:943-55.
  166. Mahmoud AM*, Soliman AS. Rutin attenuates Hyperlipidemia and Cardiac Oxidative Stress in DiabeticRats. Egy J Med Sci. 2013;34:287-302.
  167. Mahmoud AM*, Hussein OE, Ramadan SA. Amelioration of cyclophosphamide-induced hepatotoxicity bythe brown seaweed Turbenaria ornata. Int J Clin Toxicol. 2013;1:9-17.
  168. AbouRiag NBS, Mahmoud AM*, Ramadan SA. Sildenafil alleviates insulin sensitivity via attenuating oxidative stress and proinflammatory cytokines in diabetic rats. Int J Pharma Bio Sci, 2013;4(4):427-36. Scopus indexed
  169. Abdel-Moneim A, Morsy, BM, Mahmoud, AM*, Abousief, MA, Zanaty, M. Benificial therapeutic effects of Nigella sativa and Zingiber officinale in HCV patients in Egypt. EXCLI J. 2013;12:943-55.
  170. Ebaid H, Ahmed OM, Mahmoud AM, Ahmed RR. Limiting prolonged inflammation during proliferation and remodeling phases of wound healing in streptozotocin-induced diabetic rats supplemented with camel undenatured whey protein. BMC Immunol. 2013;14:31.
  171. Mahmoud AM*, […], Ashour MB. Upregulation of PPARγ mediates the antidiabetic effects of citrusflavonoids in high fat diet fed-streptozotocin induced type 2 diabetic rats. Int J Bioassays. 2013;2:756-61.
  172. Abdella EM, […], Mahmoud, AM*. Bioinformatics Analysis of Functional Genes and Proteins for the Diagnosis of Obesity-Induced Type 2 Diabetes. Int J Fundam Appl Sci. 2013;2(1):23-8.
  173. Mahmoud AM*. Influence of rutin on biochemical alterations in hyperammonemia in rats. Exp ToxicolPathol. 2012;64:783-9.
  174. Mahmoud AM*, Ahmed OM, Ashour MB, Abdel-Moneim A. Hesperidin and naringin attenuatehyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats. Journal of Diabetes and its Complications, 2012;26:483-490.
  175. Ahmed OM, Mahmoud AM*, Abdel-Moneim A, Ashour MB. Antidiabetic effects of hesperidin and naringin in type 2 diabetic rats. Diabetol Croat. 2012;41(2):53-67. Scopus indexed
  176. Ahmed OM, […], Mahmoud AM. Ameliorative Effects of Sildenafil in Acetic Acid-Induced Chronic Colitis in Rats. Life Sci J 2012;9:354-61.
  177. Abdel-Moneim A, Ashour MB, Mahmoud AM*, Ahmed OM. Insulin sensitizing effects of hesperidin and naringin in experimental model of induced type 2 diabetes: focus on tumor necrosis factor-alpha and resistin. Nat Sci. 2011;9(10):134-41.
  178. Ahmed OM, Mahmoud AM*, Abdel-Moneim A, Ashour MB. Antihyperglycemic and antihyperlipidemic effects of hesperidin and naringin in high fat diet/streptozotocin type 2 diabetic rats. Life Sci J 2011;8(4):91-101.
  179. Ahmed OM, Abdel-Moneim A, Abulyazid I, Mahmoud AM. Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in nicotinamide/streptozotocin diabetic albino rats. Diabetol Croat. 2010;39(1): 15-32.

Conference publications:

  1. Mahmoud AM, Wilkinson F, […], Arafat AM. Novel Small Molecule Glycomimetics Enhance Adipogenesis and Glucose Uptake in Adipocytes. Endocrine Reviews, 2018; 39(2:S):MON-152.
  2. Wilkinson F, Mahmoud AM, […], Alexander MY. Novel small molecule glycomimetics rescue free fatty acid-induced endothelial dysfunction via Akt/eNOS and Nrf2/ARE signaling. J Vasc Res 2017;54(S1):47.
  3. Moreno-Martinez D, Wilkinson F, McCarthy E, Mahmoud AM, Alexander MY. Endothelial Microparticles: Novel regulators of vascular calcification in vitro. Heart, 2016;102:A122-A123. DOI:10.1136/heartjnl-2016-309890.177.
  4. Wilkinson F, Mahmoud AM, […], Alexander MY. A new class of glycomimetic drugs to prevent free fatty acid-induced endothelial dysfunction. Cardiovascular Research, 2016;111(S1):S65.
  5. Wilkinson F, Mahmoud AM, […], Alexander MY. Glycomimetics; a novel class of drugs to protect against free fatty acid-induced endothelial dysfunction. Heart, 2016;102:204. DOI: 10.1136/heartjnl-2016-309890.204.
  6. Mahmoud AM, […], Alexander MY. A novel role for small molecule glycomimetics in the protection againstlipid-induced endothelial dysfunction. Heart;2015;101(6):A14. DOI:10.1136/heartjnl-2015-308734.43.
  7. Mahmoud AM, […], Alexander MY. Endothelial microparticles prevent lipid-induced endothelialdysfunction through activation of Akt/eNOS signaling pathway and attenuation of oxidative stress. Heart, 2015;101:A102. DOI:10.1136/HEARTJNL-2015-308066.180.
  8. Moreno-Martinez D, Wilkinson FL, McCarthy E, Mahmoud AM, Alexander MY. Endothelial microparticles: investigating their role on endothelial cells in vitro. Heart, 2015;101(6):A12. DOI:10.1136/heartjnl-2015-308734.36.
  9. Mahmoud AM, […], Duarte J. Protective effects of peroxisome proliferator-activated receptor (PPAR)-β activation on lipid-induced endothelial dysfunction via carnitine palmitoyl transferase-1 upregulation. Heart 2014;100(4):A9. DOI:10.1136/heartjnl-2014-306916.26.
  10. Toral M, Mahmoud AM, […], Duarte J. Chronic activation of peroxisome proliferator-activated receptor (PPAR)-β prevents endothelial dysfunction induced by high-fat diet in mice. Basic Clin Pharmacol Toxicol. 2014;115:29.

Career history