Dr Fiona Wilkinson
Dr Fiona Wilkinson
Reader
My profile
Biography
Academic and professional qualifications
PhD University of Wales (2002)
Other academic service (administration and management)
Deputy Head of Faculty Research Degrees Committee
Research Degrees Co-ordinator for Life Sciences
Theme Lead for Cardiovascular Science
Centre for Bioscience steering group committee member
DClinSci Cardiovascular units lead
REF UoA03 panel member
Co-chair of the Department of Life Sciences Athena SWAN committee
(http://www.ecu.ac.uk/equality-charters/athena-swan/ & http://www.sci-eng.mmu.ac.uk/athena_swan/women_in_science/18/)
Member of the GMO committee
External examiner roles
External examiner for intercalated BSc at Leeds University
Prizes and awards
The Annual North West Vascular meeting Oct 19
MMU Public Engagement Champion Award, 2018.
Poster prize at British Society for Cardiovascular Research 2014
Prize for best oral presentation at the CMFT R&I exhibition, Manchester (2010).
Travel feIlowship award from the British Society of Gene Therapy (2008).
Prize for best oral presentation at the European Council for Cardiovascular Research, Nice (2005).
Prize for best oral presentation at the British Society for Cardiovascular Research, Manchester
(2004).
Expert reviewer for external funding bodies
Action Medical Research
Medical Research Council
British Heart Foundation
Kidney Research UK
Visiting and honorary positions
Honorary Reader at University of Manchester
Editorial Board membership
Guest editor for Oxidative Medicine and Cellular Longevity
Membership of professional associations
Council member of the European Vascular Biology Organisation
Member of the British Society of Gene and Cell Therapy (http://www.bsgct.org/en/)
Member of the British Society for Cardiovascular Research (http://www.bscr.org)
Member of the British Atherosclerosis Society
Projects
Public engagement
European City of Science Events; Blood vessel ageing (Arndale Centre) & Women in Science- the science of cocktails event (Cane and Grain)
Manchester Science Festival
Open days for prospective students and their families
Teaching
How I’ll teach you
Vascular biology
Vascular calcification
Atherosclerosis
Endothelial repair
Microvesicles
Cellular science
Skills for Healthcare Science
Immunological techniques
Histology
Molecular biology techniques
Pathology of neurodegenerative lysosomal storage disorders
Postgraduate teaching
STP Clinical Science
MSc Biomedical Science
DClinSci
Research outputs
- Determining the pathogenic mechanisms underpinning diseases such as atherosclerosis, vascular calcification, diabetes, Lupus and neurodegenerative lysosomal storage disorders.
- Developing new therapeutic strategies to target disease including drug, gene and cell therapies.
- Investigating cell trafficking and signalling across the vessel wall from the peripheral blood to the brain and other organs following haematopoietic stem cell transplant.
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Journal articles
Pilkington, J.J., Pritchett, J., Fullwood, C., Herring, A., Wilkinson, F.L., Sheen, A.J. (2024) 'TACKoMesh – A randomised controlled trial comparing absorbable versus non-absorbable tack fixation in laparoscopic IPOM + repair of primary incisional hernia using post-operative pain and quality of life - Reliatack™ versus Protack™.' Hernia, 28(5) pp. 1879-1888.
Sidgwick, G.P., Weston, R., Mahmoud, A.M., Schiro, A., Serracino-Inglott, F., Tandel, S.M., Skeoch, S., Bruce, I.N., Jones, A.M., Alexander, M.Y., Wilkinson, F.L. (2024) 'Novel Glycomimetics Protect against Glycated Low-Density Lipoprotein-Induced Vascular Calcification In Vitro via Attenuation of the RAGE/ERK/CREB Pathway.' Cells, 13(4)
Slegg, O.G., Willis, J.A., Wilkinson, F., Sparey, J., Wild, C.B., Rossdale, J., Ross, R.M., Pauling, J.D., Carson, K., Kandan, S.R., Oxborough, D., Knight, D., Peacock, O.J., Suntharalingam, J., Coghlan, J.G., Augustine, D.X. (2022) 'IMproving PULmonary hypertension Screening by Echocardiography: IMPULSE.' Echo Research and Practice, 9(1)
Astley, C., Houacine, C., Zaabalawi, A., Wilkinson, F., Lightfoot, A.P., Alexander, Y., Whitehead, D., Singh, K.K., Azzawi, M. (2021) 'Nanostructured lipid carriers deliver resveratrol, restoring attenuated dilation in small coronary arteries, via the AMPK pathway.' Biomedicines, 9(12)
Mahmoud, A.M., Wilkinson, F.L., Lightfoot, A.P., Dos Santos, J.M., Sandhu, M.A. (2021) 'Editorial: The Role of Natural and Synthetic Antioxidants in Modulating Oxidative Stress in Drug-Induced Injury and Metabolic Disorders 2020.' Oxidative Medicine and Cellular Longevity, 2021(1)
Mahmoud, A.M., Wilkinson, F.L., Sandhu, M.A., Lightfoot, A.P. (2021) 'The Interplay of Oxidative Stress and Inflammation: Mechanistic Insights and Therapeutic Potential of Antioxidants.' Oxidative Medicine and Cellular Longevity, 2021(1)
Pang, K.T., Ghim, M., Liu, C., Tay, H.M., Fhu, C.W., Chia, R.N., Qiu, B., Sarathchandra, P., Chester, A.H., Yacoub, M.H., Wilkinson, F.L., Weston, R., Warboys, C.M., Hou, H.W., Weinberg, P.D., Wang, X. (2021) 'Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor.' Frontiers in Cell and Developmental Biology, 9pp. 706143-706143.
Pilkington, J.J., Davies, T.W., Schaff, O., Alexander, M.Y., Pritchett, J., Wilkinson, F.L., Sheen, A.J. (2021) 'Systemic biomarkers currently implicated in the formation of abdominal wall hernia: A systematic review of the literature.' American Journal of Surgery, 222(1) pp. 56-66.
Gill, D.M., Ana, A.P., Zazeri, G., Shamir, S.A., Mahmoud, A.M., Wilkinson, F.L., Alexander, M.Y., Cornelio, M.L., Jones, A.M. (2021) 'The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies.' RSC Medicinal Chemistry, 12(5) pp. 779-790.
Alexander, Y., Osto, E., Schmidt-Trucksäss, A., Shechter, M., Trifunovic, D., Duncker, D.J., Aboyans, V., Bäck, M., Badimon, L., Cosentino, F., De Carlo, M., Dorobantu, M., Harrison, D.G., Guzik, T.J., Hoefer, I., Morris, P.D., Norata, G.D., Suades, R., Taddei, S., Vilahur, G., Waltenberger, J., Weber, C., Wilkinson, F., Bochaton-Piallat, M.L., Evans, P.C. (2021) 'Endothelial function in cardiovascular medicine: A consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.' Cardiovascular Research, 117(1) pp. 29-42.
Yang, C., Eleftheriadou, M., Kelaini, S., Morrison, T., González, M.V., Caines, R., Edwards, N., Yacoub, A., Edgar, K., Moez, A., Ivetic, A., Zampetaki, A., Zeng, L., Wilkinson, F.L., Lois, N., Stitt, A.W., Grieve, D.J., Margariti, A. (2020) 'Targeting QKI-7 in vivo restores endothelial cell function in diabetes.' Nature Communications, 11(1)
Yang, C., Eleftheriadou, M., Kelaini, S., Morrison, T., González, M.V., Caines, R., Edwards, N., Yacoub, A., Edgar, K., Moez, A., Ivetic, A., Zampetaki, A., Zeng, L., Wilkinson, F.L., Lois, N., Stitt, A.W., Grieve, D.J., Margariti, A. (2020) 'Author Correction: Targeting QKI-7 in vivo restores endothelial cell function in diabetes (Nature Communications, (2020), 11, 1, (3812), 10.1038/s41467-020-17468-y).' Nature Communications, 11(1)
Bartoli-Leonard, F., Wilkinson, F.L., Schiro, A., Inglott, F.S., Alexander, M.Y., Weston, R. (2020) 'Loss of SIRT1 in diabetes accelerates DNA damage induced vascular calcification.' Cardiovascular Research, 117(3) pp. 836-849.
Parker, H., Ellison, S.M., Holley, R.J., O'Leary, C., Liao, A., Asadi, J., Glover, E., Ghosh, A., Jones, S., Wilkinson, F.L., Brough, D., Pinteaux, E., Boutin, H., Bigger, B.W. (2020) 'Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA.' EMBO Molecular Medicine, 12(3)
Langford-Smith, A.W.W., Hasan, A., Weston, R., Edwards, N., Jones, A.M., Boulton, A.J.M., Bowling, F.L., Rashid, S.T., Wilkinson, F.L., Alexander, M.Y. (2019) 'Diabetic endothelial colony forming cells have the potential for restoration with glycomimetics.' Scientific Reports, 9(1)
Mitsides, N., Alsehli, F.M.S., Mc Hough, D., Shalamanova, L., Wilkinson, F., Alderdice, J., Mitra, R., Swiecicka, A., Brenchley, P., Parker, G.J.M., Alexander, M.Y., Mitra, S. (2019) 'Salt and Water Retention Is Associated with Microinflammation and Endothelial Injury in Chronic Kidney Disease.' Nephron, 143(4) pp. 234-242.
Mahmoud, A.M., Jones, A.M., Sidgwick, G.P., Arafat, A.M., Alexander, Y.M., Wilkinson, F.L. (2019) 'Small Molecule Glycomimetics Inhibit Vascular Calcification via c-Met/Notch3/HES1 Signalling.' Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 53(2) pp. 323-336.
Yu, K., Youshani, A.S., Wilkinson, F.L., O'Leary, C., Cook, P., Laaniste, L., Liao, A., Mosses, D., Waugh, C., Shorrock, H., Pathmanaban, O., Macdonald, A., Kamaly-Asl, I., Roncaroli, F., Bigger, B.W. (2019) 'A non-myeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma..' Neuropathology and Applied Neurobiology, 45(2) pp. 119-140.
Bartoli-Leonard, F., Wilkinson, F.L., Schiro, A., Inglott, F.S., Alexander, M.Y., Weston, R. (2019) 'Suppression of SIRT1 in Diabetic Conditions Induces Osteogenic Differentiation of Human Vascular Smooth Muscle Cells via RUNX2 Signalling.' Scientific Reports, 9(1)
Mahmoud, A.M., Wilkinson, F.L., Sandhu, M.A., Dos Santos, J.M., Yvonne Alexander, M. (2019) 'Modulating oxidative stress in drug-induced injury and metabolic disorders: The role of natural and synthetic antioxidants.' Oxidative Medicine and Cellular Longevity, 2019
Bartoli-Leonard, F., Wilkinson, F.L., Langford-Smith, A.W.W., Alexander, M.Y., Weston, R. (2018) 'The Interplay of SIRT1 and Wnt Signaling in Vascular Calcification.' Frontiers in Cardiovascular Medicine, 5
Edwards, N., Langford-Smith, A., Parker, B., Bruce, I., Reynolds, J., Alexander, Y., McCarthy, E., Wilkinson, F. (2018) 'QRISK3 improves detection of cardiovascular disease risk in patients with systemic lupus erythematosus.' Lupus Science & Medicine, 5(1) pp. 1-6.
Edwards, N., Langford-Smith, A.W.W., Wilkinson, F.L., Alexander, M.Y. (2018) 'Endothelial Progenitor Cells: New Targets for Therapeutics for Inflammatory Conditions With High Cardiovascular Risk..' Frontiers in medicine, 5pp. 1-11.
Holley, R.J., Ellison, S.M., Fil, D., O'Leary, C., McDermott, J., Senthivel, N., Langford-Smith, A., Wilkinson, F.L., D'Souza, Z., Parker, H., Liao, A., Rowlston, S., Gleitz, H., Kan, S., Dickson, P., Bigger, B.W. (2018) 'Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.' Brain, 141(1) pp. 99-116.
Mahmoud, A.M., Alexander, M.Y., Tutar, Y., Wilkinson, F.L., Venditti, A. (2017) 'Oxidative Stress in Metabolic Disorders and Drug-Induced Injury: The Potential Role of Nrf2 and PPARs Activators.' Oxidative Medicine and Cellular Longevity, 2017pp. 1-4.
Mahmoud, A.M., Wilkinson, F.L., McCarthy, E.M., Moreno-Martinez, D., Langford-Smith, A., Romero, M., Duarte, J., Alexander, M.Y. (2017) 'Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress..' The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(10) pp. 4636-4648.
Satta, S., Mahmoud, A.M., Wilkinson, F.L., Alexander, Y., White, S.J. (2017) 'The Role of Nrf2 in Cardiovascular Function and Disease.' Oxidative Medicine and Cellular Longevity, 2017
McCarthy, E.M., Moreno-Martinez, D., Wilkinson, F.L., McHugh, N.J., Bruce, I.N., Pauling, J.D., Alexander, Y., Parker, B. (2017) 'Microparticle subpopulations are potential markers of disease progression and vascular dysfunction across a spectrum of connective tissue disease.' BBA Clinical, 7pp. 16-22.
Mahmoud, A.M., Wilkinson, F., Wilkinson, J.A., Romero, M., Duarte, J., Alexander, Y., Jones, A.M. (2016) 'A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: involvement of Akt/eNOS and Nrf2/ARE signaling.' Biochimica et Biophysica Acta (BBA) - General Subjects, 1861(1) pp. 3311-3322.
Wilkinson, F.L., Mahmoud, A.M., Jones, A.M., Wilkinson, J.A., Romero, M., Duarte, J., Alexander, M.Y. (2016) 'A new class of glycomimetic drugs to prevent free fatty acid-induced endothelial dysfunction.' Cardiovascular Research, 111(S1) pp. S65-S65.
McCarthy, E.M., Wilkinson, F.L., Parker, B., Alexander, M.Y. (2016) 'Endothelial microparticles: Pathogenic or passive players in endothelial dysfunction in autoimmune rheumatic diseases?.' Vascular Pharmacology, 86pp. 71-76.
Schiro, A., Wilkinson, F.L., Weston, R., Smyth, J.V., Serracino-Inglott, F., Alexander, M.Y. (2015) 'Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques..' Scientific Reports, 5
Weston, R., Sidgwick, G.P., Ahmed, N., Nazhad, N., Schiro, A., Wilkinson, F.L., Alexander, M.Y. (2015) 'Glycation and vascular calcification: developing an anti-calcification strategy.' Heart, 101pp. A14-A14.
Martins, C., Hulková, H., Dridi, L., Dormoy-Raclet, V., Grigoryeva, L., Choi, Y., Langford-Smith, A., Wilkinson, F.L., Ohmi, K., DiCristo, G., Hamel, E., Ausseil, J., Cheillan, D., Moreau, A., Svobodová, E., Hájková, Z., Tesarǒvá, M., Hansíková, H., Bigger, B.W., Hrebícek, M., Pshezhetsky, A.V. (2015) 'Erratum: Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model ((Brain (2015) DOI: 10.1093/brain/awu355).' Brain, 138(7)
Martins, C., Hulkova, H., Dridi, L., Dormoy-Raclet, V., Grigoryeva, L., Choi, Y., Langford-Smith, A., Wilkinson, F.L., Ohmi, K., DiCristo, G., Hamel, E., Ausseil, J., Cheillan, D., Moreau, A., Svobodova, E., Hajkova, Z., Tesarova, M., Hansikova, H., Bigger, B.W., Hrebicek, M., Pshezhetsky, A.V. (2015) 'Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model.' Brain, 138
Watson, H.A., Holley, R.J., Langford-Smith, K.J., Wilkinson, F.L., Van Kuppevelt, T.H., Wynn, R.F., Wraith, J.E., Merry, C.L.R., Bigger, B.W. (2014) 'Heparan Sulfate Inhibits Hematopoietic Stem and Progenitor Cell Migration and Engraftment in Mucopolysaccharidosis I.' Journal of Biological Chemistry, 289(52) pp. 36194-36203.
Ndip, A., Wilkinson, F.L., Jude, E.B., Boulton, A.J.M., Alexander, M.Y. (2014) 'RANKL-OPG and RAGE modulation in vascular calcification and diabetes: novel targets for therapy..' Diabetologia, 57(11) pp. 2251-2260.
Schiro, A., Wilkinson, F.L., Weston, R., Smyth, J.V., Serracino-Inglott, F., Alexander, M.Y. (2014) 'Endothelial microparticles as conveyors of information in atherosclerotic disease..' Atherosclerosis, 234(2) pp. 295-302.
Langford-Smith, K.J., Sandiford, Z., Langford-Smith, A., Wilkinson, F.L., Jones, S.A., Wraith, J.E., Wynn, R.F., Bigger, B.W. (2013) 'Signal One and Two Blockade Are Both Critical for Non-Myeloablative Murine HSCT across a Major Histocompatibility Complex Barrier.' PLoS ONE, 8(10)
Sergijenko, A., Langford-Smith, A., Liao, A.Y., Pickford, C.E., McDermott, J., Nowinski, G., Langford-Smith, K.J., Merry, C.L., Jones, S.A., Wraith, J.E., Wynn, R.F., Wilkinson, F.L., Bigger, B.W. (2013) 'Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease.' Molecular Therapy, 21(10) pp. 1938-1949.
Denes, A., Wilkinson, F., Bigger, B., Chu, M., Rothwell, N.J., Allan, S.M. (2013) 'Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice.' DMM Disease Models and Mechanisms, 6(4) pp. 1043-1048.
Wilkinson, F.L., Sergijenko, A., Langford-Smith, K.J., Malinowska, M., Wynn, R.F., Bigger, B.W. (2013) 'Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation.' MOLECULAR THERAPY, 21(4) pp. 868-876.
Wilkinson, F.L., Sergijenko, A., Langford-Smith, K.J., Malinowska, M., Wynn, R.F., Bigger, B.W. (2013) 'Erratum: Busulfan conditioning enhances engraftment of hematopoietic donor-derived cells in the brain compared with irradiation (Molecular Therapy (2013) 21 (868-876) DOI: 10.1038/mt.2013.29).' Molecular Therapy, 21(7)
Langford-Smith, A., Wilkinson, F.L., Langford-Smith, K.J., Holley, R.J., Sergijenko, A., Howe, S.J., Bennett, W.R., Jones, S.A., Wraith, J.E., Merry, C.L., Wynn, R.F., Bigger, B.W. (2012) 'Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice..' Molecular therapy : the journal of the American Society of Gene Therapy, 20(8) pp. 1610-1621.
Wilkinson, F.L., Holley, R.J., Langford-Smith, K.J., Badrinath, S., Liao, A., Langford-Smith, A., Cooper, J.D., Jones, S.A., Wraith, J.E., Wynn, R.F., Merry, C.L.R., Bigger, B.W. (2012) 'Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB.' PLOS ONE, 7(4)
Langford-Smith, A., Wilkinson, F.L., Langford-Smith, K.J., Holley, R.J., Sergijenko, A., Howe, S.J., Bennett, W.R., Jones, S.A., Wraith, J.E., Merry, C.L.R., Wynn, R.F., Bigger, B.W. (2012) 'Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice.' MOLECULAR THERAPY, 20(8) pp. 1610-1621.
Langford-Smith, A., Langford-Smith, K.J., Jones, S.A., Wynn, R.F., Wraith, J.E., Wilkinson, F.L., Bigger, B.W. (2011) 'Female Mucopolysaccharidosis IIIA Mice Exhibit Hyperactivity and a Reduced Sense of Danger in the Open Field Test.' PLOS ONE, 6(10)
Langford-Smith, A., Malinowska, M., Langford-Smith, K.J., Wegrzyn, G., Jones, S., Wynn, R., Wraith, J.E., Wilkinson, F.L., Bigger, B.W. (2011) 'Hyperactive behaviour in the mouse model of mucopolysaccharidosis IIIB in the open field and home cage environments.' GENES BRAIN AND BEHAVIOR, 10(6) pp. 673-682.
Malinowska, M., Wilkinson, F.L., Langford-Smith, K.J., Langford-Smith, A., Brown, J.R., Crawford, B.E., Vanier, M.T., Grynkiewicz, G., Wynn, R.F., Wraith, J.E., Wegrzyn, G., Bigger, B.W. (2010) 'Genistein Improves Neuropathology and Corrects Behaviour in a Mouse Model of Neurodegenerative Metabolic Disease.' PLOS ONE, 5(12)
Canal, M.M., Wilkinson, F.L., Cooper, J.D., Wraith, J.E., Wynn, R., Bigger, B.W. (2010) 'Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB.' BEHAVIOURAL BRAIN RESEARCH, 209(2) pp. 212-220.
Malinowska, M., Wilkinson, F.L., Bennett, W., Langford-Smith, K.J., O'Leary, H.A., Jakobkiewicz-Banecka, J., Wynn, R., Wraith, J.E., Wegrzyn, G., Bigger, B.W. (2009) 'Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice.' MOLECULAR GENETICS AND METABOLISM, 98(3) pp. 235-242.
Alam, M.U., Kirton, J.P., Wilkinson, F.L., Towers, E., Sinha, S., Rouhi, M., Vizard, T.N., Sage, A.P., Martin, D., Ward, D.T., Alexander, M.Y., Riccardi, D., Canfield, A.E. (2009) 'Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells.' CARDIOVASCULAR RESEARCH, 81(2) pp. 260-268.
Liu, Y., Wilkinson, F.L., Kirton, J.P., Jeziorska, M., Iizasa, H., Sai, Y., Nakashima, E., Heagerty, A.M., Canfield, A.E., Alexander, M.Y. (2007) 'Hepatocyte growth factor and c-Met expression in pericytes: implications for atherosclerotic plaque development.' JOURNAL OF PATHOLOGY, 212(1) pp. 12-19.
Wilkinson, F.L., Liu, Y., Rucka, A.K., Jeziorska, M., Hoyland, J.A., Heagerty, A.M., Canfield, A.E., Alexander, M.Y. (2007) 'Contribution of VCAF-positive cells to neovascularization and calcification in atherosclerotic plaque development.' JOURNAL OF PATHOLOGY, 211(3) pp. 362-369.
Canfield, A.E., Hadfield, K.D., Rock, C.F., Wylie, E.C., Wilkinson, F.L. (2007) 'HtrA1: a novel regulator of physiological and pathological matrix mineralization?.' BIOCHEMICAL SOCIETY TRANSACTIONS, 35pp. 669-671.
Kirton, J.P., Wilkinson, F.L., Canfield, A.E., Alexander, M.Y. (2006) 'Dexamethasone downregulates calcification-inhibitor molecules and accelerates osteogenic differentiation of vascular pericytes implications for vascular calcification.' CIRCULATION RESEARCH, 98(10) pp. 1264-1272.
Alexander, M.Y., Wilkinson, F.L., Kirton, J.P., Rock, C.F., Collett, G.D.M., Jeziorska, M., Smyth, J.V., Heagerty, A.M., Canfield, A.E. (2005) 'Identification and characterization of vascular calcification-associated factor, a novel gene upregulated during vascular calcification in vitro and in vivo.' ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(9) pp. 1851-1857.
Wilkinson, F.L., Holaska, J.M., Zhang, Z., Sharma, A., Manilal, S., Holt, I., Stamm, S., Wilson, K.L., Morris, G.E. (2003) 'Emerin interacts in vitro with the splicing-associated factor, YT521-B.' European Journal of Biochemistry, 270(11) pp. 2459-2466.
Wilkinson, F.L., Thi Man, N., Manilal, S.B., Thomas, P., Neal, J.W., Harper, P.S., Jones, A.L., Morris, G.E. (1999) 'Localization of rabbit huntingtin using a new panel of monoclonal antibodies.' Molecular Brain Research, 69(1) pp. 10-20.
Thomas, P., Wilkinson, F., Man, N.T., Harper, P.S., Neal, J.W., Morris, G.E., Lesley Jones, A. (1998) 'Full length huntingtin is not detected in intranuclear inclusions in Huntington's disease brain.' Biochemical Society Transactions, 26(3)
Man, N.T., Manilal, S.B., Wilkinson, F.L., Chan, P.N.Y., Morris, G.E. (1997) 'Monoclonal antibody studies of emery-dreifuss muscular dystrophy, myotonic dystrophy and huntington's disease gene products.' FASEB Journal, 11(9)
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Conference papers
Ellison, S.M., Parker, H., Holley, R., O'Leary, C., Liao, A., Asadi, J., Glover, E., Ghosh, A., Jones, S., Wilkinson, F.L., Brough, D., Pinteaux, E., Boutin, H., Bigger, B. (2020) 'Haematopoietic Stem Cell Gene Therapy with IL-1Ra Prevents Cognitive Loss in Mucopolysaccharidosis IIIA Mice.' In 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy. 28. ELECTR NETWORK, 12/5/2020 - 15/5/2020. CELL PRESS, pp. 306-306.
Edwards, N., Langford-Smith, A.W., Tandel, S., Parker, B., Bruce, I., Reynolds, J.A., Alexander, M.Y., McCarthy, E., Wilkinson, F.L. (2019) 'Improving patient stratification in systemic lupus erythematosus using endothelial microvesicles as novel biomarkers of cardiovascular risk.' 9. WILEY, pp. 103-103.
Edwards, N., Langford-Smith, A.W.W., Floren, M., Hasan, A., Weston, R., Rashid, S.T., Boulton, A., Bowling, F., Tan, W., Wilkinson, F.L., Alexander, M.Y. (2019) 'Mitochondrial Hyperactivity, Impaired Matrix Adhesion and Functional Activity in Endothelial Colony Forming Cells Isolated from Patients with Diabetic Foot Ulcers.' 33. SPRINGER, pp. 273-273.
Alexander, Y., Langford-Smith, A.W., Hassan, A., Edwards, N., Wilkinson, F.L. (2019) 'Endothelial Dysfunction in the Diabetic Patient and the Contribution by Circulating Endothelial Colony Forming Cells.' In 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO). 56. Maastricht, NETHERLANDS, 15/4/2019 - 18/4/2019. KARGER, pp. 3-3.
Astley, C., Houacine, C., Wilkinson, F.L., Lightfoot, A., Singh, K., Whitehead, D., Alexander, Y., Azzawi, M. (2019) 'Resveratrol-Loaded Nanostructured Lipid Carriers Restore Dilator Function Following Acute Pressure Elevation, Ex Vivo.' In 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO). 56. Maastricht, NETHERLANDS, 15/4/2019 - 18/4/2019. KARGER, pp. 7-7.
Edwards, N., Langford-Smith, A.W., Tandel, S., Parker, B., Bruce, I., Reynolds, J., Alexander, Y., McCarthy, E., Wilkinson, F.L. (2019) 'Improving Stratification of Cardiovascular Risk in Systemic Lupus Erythematosus using Endothelial Microvesicles as Novel Biomarkers.' In 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO). 56. Maastricht, NETHERLANDS, 4/2019 - KARGER, pp. 32-33.
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